Growing pains (GP) is the most common musculoskeletal complaint in childhood. The present study describes the development, validation and clinical evaluation of a questionnaire for the detection of GP in the general children's population aged 4 -7 years of age. Based on the existing publications, a 27-point closed type questionnaire was developed and was administered to a parental population of school-age children for standardization. Nine questions evaluating pain localization, intensity and 24-hour temporal distribution, exhibited excellent validity and reliability and were finally selected. A cut-off point of ? 8 was proposed for GP's diagnosis. Questionnaire's sensitivity and specificity were studied in a sample of outpatient children attending an orthopedic clinic for lower limb pain of no apparent traumatic origin. The diagnosis of GP based on the questionnaire coincided with the orthopedic diagnosis in all cases. The proposed questionnaire is a reliable and valid screening tool for GP.

Download full-text PDF

Source

Publication Analysis

Top Keywords

screening tool
8
growing pains
8
clinical evaluation
8
development screening
4
tool children's
4
children's growing
4
pains validation
4
validation reliability
4
reliability control
4
control clinical
4

Similar Publications

Modular assembly of amines and diborons with photocatalysis enabled halogen atom transfer of organohalides for C(sp)-C(sp) bond formation.

Chem Sci

January 2025

College of Chemistry and Chemical Engineering, Key (Guangdong-Hong Kong Joint) Laboratory for Preparation and Application of Ordered Structural Materials of Guangdong Province, Shantou University Shantou 515063 P. R. China

In the past few years, the direct activation of organohalides by ligated boryl radicals has emerged as a potential synthetic tool for cross-coupling reactions. In most existing methods, ligated boryl radicals are accessed from NHC-boranes or amine-boranes. In this work, we report a new photocatalytic platform by modular assembly of readily available amines and diboron esters to access a library of ligated boryl radicals for reaction screening, thus enabling the cross-coupling of organohalides and alkenes including both activated and unactivated ones for C(sp)-C(sp) bond formation by using the assembly of DABCO A1 and BNepB1.

View Article and Find Full Text PDF

Objective: To understand the current status and analyse the factors influencing frailty in older adults patients with pulmonary tuberculosis.

Methods: This retrospective case-control study included 204 older adults patients with pulmonary tuberculosis. The enrolled patients were divided into a frailty group (n = 101) and a non-frailty group (n = 103).

View Article and Find Full Text PDF

Introduction: The establishment of a high-throughput quantification approach for waterborne pathogenic protozoa and helminths is crucial for rapid screening and health risk assessment.

Methods: We developed a high-throughput quantitative polymerase chain reaction (HT-qPCR) assay targeting 19 waterborne protozoa and 3 waterborne helminths and validated its sensitivity, specificity, and repeatability. The assay was then applied to test various environmental media samples.

View Article and Find Full Text PDF

A genetically encoded fluorescent biosensor for sensitive detection of cellular c-di-GMP levels in .

Front Chem

January 2025

Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, East China University of Science and Technology, Shanghai, China.

Cyclic di-guanosine monophosphate (c-di-GMP) acts as a second messenger regulating bacterial behaviors including cell cycling, biofilm formation, adhesion, and virulence. Monitoring c-di-GMP levels is crucial for understanding these processes and designing inhibitors to combat biofilm-related antibiotic resistance. Here, we developed a genetically encoded biosensor, cdiGEBS, based on the transcriptional activity of the c-di-GMP-responsive transcription factor MrkH.

View Article and Find Full Text PDF

Background: Lipid Accumulation Product (LAP), which is derived from measurements of waist circumference and triglyceride (TG) levels, serves as a comprehensive indicator of lipid accumulation. Emerging research indicates that lipid accumulation dysfunction might significantly contribute to the pathogenesis of Chronic Obstructive Pulmonary Disease (COPD). Nevertheless, the investigation into the association between LAP and COPD risk is still insufficient, particularly in population-based research.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!