AI Article Synopsis
- The study evaluated genetic variations among Schistosoma japonicum isolates from different locations in Yunnan Province, China, using mitochondrial genes.
- PCR amplification and sequencing unveiled varying nucleotide differences across different strains, with the most significant variation found in col, followed by nd1 and nd6.
- Phylogenetic analysis suggested that the isolates were genetically similar to each other and were closer to S. malayensis and S. mekongi than to other species like S. haematobium or S. mansoni, indicating col, nd1, and nd6 are better markers for distinguishing these species.
Article Abstract
In order to evaluate differentiate genetic differences among Schistosoma japonicum isolates from Dali Ancient City, Xizhou and Yongsheng County, Yunnan Province, China, mitochondrial col, cytb, nd1, nd6, and nd4l were PCR amplified and sequenced, revealing nucleotide difference(s) among these strains of 8, 1, 5, 4, and 0, respectively. Phylogenetic analysis showed that S. japonicum from the three different geographical locations of Yunnan Province were clustered genetically together and were more similar to S. malayensis and S. mekongi than S. haematobium or S. mansoni. For intra-species differentiation purposes, Schistosoma mitochondrial col, nd1, and nd6 are better genetic markers than cytb and nd41.
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