Taking Centrioles to the Elimination Round.

Dev Cell

Cell Biology and Physiology Center, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

Published: July 2016

AI Article Synopsis

  • Two recent studies have explored how centrioles are eliminated during the process of female oogenesis.
  • They found that Polo kinase plays a protective role in this elimination process.
  • The research also emphasizes the importance of pericentriolar material in facilitating centriole removal.

Article Abstract

Two recent papers published in The Journal of Cell Biology (Borrego-Pinto et al., 2016) and Science (Pimenta-Marques et al., 2016) have begun to shed light on the mechanism of centriole elimination during female oogenesis, highlighting a protective role for Polo kinase and the pericentriolar material.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027879PMC
http://dx.doi.org/10.1016/j.devcel.2016.06.027DOI Listing

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