AI Article Synopsis

  • Paecilomyces variotii can cause infections in both immunocompromised and healthy individuals, but cases are rare, leading to limited research on effective treatments.
  • A patient with pneumonia caused by this fungus was successfully treated with posaconazole after initial treatment with voriconazole failed.
  • The paper reviews existing literature on how to identify the fungus, its antifungal susceptibility, and strategies for managing infections from P. variotii.

Article Abstract

The fungi Paecilomyces variotii is a potential pathogen in immunocompromised and immunocompetent patients. Their rare association with clinical disease results in scarce literature regarding susceptibility and treatment. Here, we discuss a case involving successful treatment of probable P. variotii pneumonia with posaconazole after treatment failure with voriconazole. The current literature related to antifungal susceptibility profiles, microbiological identification methods and clinical management of infections caused by this organism is also reviewed.

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http://dx.doi.org/10.1111/myc.12525DOI Listing

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