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Role of Small Airways in Asthma. | LitMetric

Role of Small Airways in Asthma.

Immunol Allergy Clin North Am

Department of Medicine, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, USA.

Published: August 2016

AI Article Synopsis

  • Asthma is characterized by inflammation in both small and large airways, with significant attention on small airways due to their role in varying severities of the condition.
  • Recent studies have linked inflammation in small airways to increased airway resistance, highlighting the need for reliable noninvasive measurement methods.
  • Innovations in asthma inhalers, including new drug formulations and extrafine particle inhalers, have improved drug delivery to the smaller, distal airways.

Article Abstract

Asthma is an inflammatory condition of both the small and large airways. Recently the small airways have gained attention as studies have shown significant inflammation in the small airways in all severities of asthma. This inflammation has correlated with peripheral airway resistance and as a result, noninvasive methods to reliably measure small airways have been pursued. In addition, recent changes in asthma inhalers have led to alterations in drug formulations and the development of extrafine particle inhalers that improve delivery to the distal airways.

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Source
http://dx.doi.org/10.1016/j.iac.2016.03.009DOI Listing

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