Radical Smiles Rearrangement: An Update.

Molecules

Institut de Chimie Moléculaire de Reims, UMR CNRS 7312, Université de Reims-Champagne-Ardenne, Faculté de Pharmacie, 51 rue Cognacq-Jay, F-51096 Reims Cedex, France.

Published: July 2016

Over the decades the Smiles rearrangement and its variants have become essential synthetic tools in modern synthetic organic chemistry. In this mini-review we summarized some very recent results of the radical version of these rearrangements. The selected examples illustrate the synthetic power of this approach, especially if it is incorporated into a domino process, for the preparation of polyfunctionalized complex molecules.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273782PMC
http://dx.doi.org/10.3390/molecules21070878DOI Listing

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