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Assessing the Long-Term Effectiveness of Fractional CO Laser Treatment in Perimenopausal Women with Genitourinary Syndrome of Menopause-Single Center Preliminary Study.
J Clin Med
January 2025
2nd Chair and Department of Gynecology, Medical University of Lublin, Jaczewskiego 8, 20-954 Lublin, Poland.
Genitourinary Syndrome of Menopause (GSM) is a prevalent condition in postmenopausal women characterized by symptoms such as vaginal dryness, itching, and urinary tract issues due to declining estrogen levels. Despite its widespread impact on quality of life, GSM often remains underdiagnosed and without effective treatment. This study assessed the long-term efficacy of fractional CO laser treatment in alleviating GSM symptoms in perimenopausal women.
View Article and Find Full Text PDFPhysiological, Photosynthetic Characteristic and Transcriptome Analysis of Transgenic × Under Salt Stress.
Int J Mol Sci
December 2024
College of Forestry, Henan Agricultural University, Zhengzhou 450002, China.
The WRKY70 transcription factor (TF) was reported to play an important role in the salt stress response mechanism of in our previous research, and we also produced several overexpression (OEXs) and RNAi suppression (REXs) × lines. In order to further compare the photosynthetic and physiological characteristics of NT (non-transgenic line) and transgenic lines under salt stress, the dynamic phenotypic change, Na and K content in leaf and root tissues, superoxide dismutase (SOD) and peroxidase (POD) activity, malondialdehyde (MDA) content, chlorophyll content (Chl), photosynthesis parameters (net photosynthetic rate, P; stomatal conductance, Gs; intercellular CO concentration, C; transpiration rate, T), chlorophyll fluorescence parameters (electron transport rate, ETR; maximum photochemical efficiency of photosystem II (PSII), F/F; actual efficiency of PSII, Φ; photochemical quenching coefficient, q; non-photochemical quenching, NPQ; the photosynthetic light-response curves of Φ and ETR) and RNA-seq of NT, OEX and REX lines were detected and analyzed. The phenotypic observation, MDA content and Chl detection results indicate that the stress damage of REXs was less severe than that of NT and OEX lines under salt stress.
View Article and Find Full Text PDFHighly Active Carbonic Anhydrase of the Thylakoid Lumen of .
Plants (Basel)
December 2024
Institute of Basic Biological Problems, Federal Research Center "Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences", 142290 Pushchino, Russia.
The green unicellular algae contains 12-13 carbonic anhydrases (CAs). For a long time, the two closely related α-CAs of the periplasmic membrane CAH1 and CAH2 were considered to be the CAs with the highest CO hydration activity. The recombinant protein α-CA CAH3 (rCAH3) from the thylakoid lumen obtained in the present study showed more than three times higher activity compared to CAH1 and more than 11 times higher compared to previous studies with rCAH3.
View Article and Find Full Text PDFFunctional and oncological outcomes of transoral laser versus robotic surgery in supraglottic squamous cell carcinoma.
Oral Oncol
January 2025
Department of Otolaryngology - Head & Neck Surgery Foch Hospital Suresnes France; School of Medicine, UFR Simone Veil, Université Versailles Saint-Quentin-en-Yvelines (Paris Saclay University), 2 Av. de la Source de la Bièvre 78 180 Montigny-le-Bretonneux, France; Phonetics and Phonology Laboratory (UMR 7018 CNRS & Université Sorbonne nouvelle), Paris, France.
Objective: To compare the surgical, functional and oncological outcomes of Transoral Laser Microsurgery (TLM) and Transoral Robotic Surgery (TORS) for the treatment of supraglottic squamous cell carcinoma.
Study Design: Retrospective case series with prospective data.
Settings: Tertiary Academic Medical Center.
Unveiling hidden reaction kinetics of carbon dioxide in supercritical aqueous solutions.
Proc Natl Acad Sci U S A
January 2025
Department of Physics, The Hong Kong University of Science and Technology, Hong Kong, China.
Dissolution of CO in water followed by the subsequent hydrolysis reactions is of great importance to the global carbon cycle, and carbon capture and storage. Despite numerous previous studies, the reactions are still not fully understood at the atomistic scale. Here, we combined ab initio molecular dynamics (AIMD) simulations with Markov state models to elucidate the reaction mechanisms and kinetics of CO in supercritical water both in the bulk and nanoconfined states.
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