The rich flat bug fauna of Madagascar comprises eleven apterous genera of Mezirinae with 21 species (Heiss 2012, Heiss & Marchal 2012) to date, and all of them are endemic: Ambohitantelya Heiss & Baňař 2013 (1 sp.); Antsirabenus Heiss 2008 (2 spp.); Cervinotaptera Heiss & Marchal 2012 (1 sp.); Chlonocoris Usinger & Matsuda 1959 (3 spp.); Cimicomanes Kiritshenko 1959 (5 spp.); Classeyana Hoberlandt 1963 (1 sp.); Paulianum Hoberlandt 1957 (1 sp.); Pericartaptera Heiss 2009 (2 spp.); Ribesaptera Heiss 2011 (1 sp.); Robertiessa Hoberlandt 1963 (1 sp.) and Tananarivea Drake 1957 (3 spp.).
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http://dx.doi.org/10.11646/zootaxa.4088.1.9 | DOI Listing |
Viruses
January 2025
Surgical Neurology Branch, NINDS, NIH 10 Center Drive, Bethesda, MD 20892, USA.
Glioblastoma multiforme (GBM) is a devastating, aggressive primary brain tumor with poor patient outcomes and a five-year survival of less than 10%. Significant limitations to effective GBM treatment include poor drug delivery across the blood-brain barrier, drug resistance, and complex genetic tumor alterations. Gene therapy uses a mechanism different from other GBM therapies to reduce tumor growth and enhance antitumor immunity.
View Article and Find Full Text PDFJ Hematol Oncol
January 2025
Experimentelle Unfallchirurgie (ForMED), Justus-Liebig-Universität Gießen, Aulweg 128, 35392, Gießen, Germany.
Vet Sci
January 2025
Department of Animal Science, Universidade Federal de Viçosa, University Campus, Viçosa 36570-900, Brazil.
This study evaluated the effects of two types of plastic flooring-one with and one without nanotechnological antimicrobial additives-used as complete or partial replacements for wood shavings on broiler chicken performance, yield, meat quality, and litter microbiology over 42 days. A total of 1500 Ross 408 male broiler chicks were randomly assigned to five treatment groups: wood shavings (WS), plastic flooring (PF), a 50/50 mix of plastic flooring and wood shavings (PF + WS), plastic flooring with antimicrobial additives (PFA), and a 50/50 mix of antimicrobial plastic flooring and wood shavings (PFA + WS). This study evaluated organ biometrics (liver, heart, spleen, and gizzard), the severity of lesions, microbiological profiles, performance indices, and meat quality.
View Article and Find Full Text PDFNat Commun
January 2025
Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, KY, USA.
Streptococcus mutans, the causative agent of human dental caries, expresses a cell wall attached Serotype c-specific Carbohydrate (SCC) that is critical for cell viability. SCC consists of a polyrhamnose backbone of →3)α-Rha(1 → 2)α-Rha(1→ repeats with glucose (Glc) side-chains and glycerol phosphate (GroP) decorations. This study reveals that SCC has one predominant and two more minor Glc modifications.
View Article and Find Full Text PDFJNCI Cancer Spectr
January 2025
Section on Medical Neuroendocrinology National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, 20892, MD, USA.
Head and neck paragangliomas (HNPGLs) are typically slow-growing, hormonally inactive tumors of parasympathetic paraganglia. Inactivation of prolyl-hydroxylase domain-containing 2 protein causing indirect gain-of-function of hypoxia-inducible factor-2α (HIF-2α), encoded by EPAS1, was recently shown to cause carotid body hyperplasia. We previously described a syndrome with multiple sympathetic paragangliomas caused by direct gain-of-function variants in EPAS1 (Pacak-Zhuang syndrome, PZS) and developed a corresponding mouse model.
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