In this paper, we propose novel methods that are more suitable than classical large-margin classifiers for open set recognition and object detection tasks. The proposed methods use the best fitting hyperplanes approach, and the main idea is to find the best fitting hyperplanes such that each hyperplane is close to the samples of one of the classes and is as far as possible from the other class samples. To this end, we propose two different classifiers: The first classifier solves a convex quadratic optimization problem, but negative samples can lie on one side of the best fitting hyperplane. The second classifier, however, allows the negative samples to lie on both sides of the fitting hyperplane by using concave-convex procedure. Both methods are extended to the nonlinear case by using the kernel trick. In contrast to the existing hyperplane fitting classifiers in the literature, our proposed methods are suitable for large-scale problems, and they return sparse solutions. The experiments on several databases show that the proposed methods typically outperform other hyperplane fitting classifiers, and they work as good as the SVM classifier in classical recognition tasks. However, the proposed methods significantly outperform SVM in open set recognition and object detection tasks.
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PLoS One
January 2025
Department of Radiation Physics, Zhejiang Key Laboratory of Radiation Oncology, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang, China.
Accurate and efficient automatic segmentation is essential for various clinical tasks such as radiotherapy treatment planning. However, atlas-based segmentation still faces challenges due to the lack of representative atlas dataset and the computational limitations of deformation algorithms. In this work, we have proposed an atlas selection procedure (subset atlas grouping approach, MAS-SAGA) which utilized both image similarity and volume features for selecting the best-fitting atlases for contour propagation.
View Article and Find Full Text PDFPatient Prefer Adherence
January 2025
Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Background: Treatment guidelines recommend metformin as initial drug in many people with type 2 diabetes (T2D) and low risk of cardiovascular disease, with the possibility to switch to or add other drug classes. A decision aid (DA) could be useful to incorporate a patient's preferences in the decision of which drug class to choose. We developed such a DA and assessed the perspectives of people with T2D towards its comprehensibility and usability.
View Article and Find Full Text PDFFront Med (Lausanne)
January 2025
Department of Ophthalmology and Visual Sciences, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Background: Federally Qualified Health Centers (FQHCs) are safety-net primary health care clinics in the US serving medically underserved areas and populations. We administered the National Eye Institute Visual Function Questionnaire - 9 (VFQ-9), a vision-targeted, health-related quality of life questionnaire, to patients in 3 FQHCs in rural Alabama at risk for glaucoma. We examined demographic factors and self-reported eye conditions associated with VFQ-9 scores.
View Article and Find Full Text PDFRate equations and numerical simulations relying on complex mathematical and physical principles are typically used to model directly modulated lasers (DMLs) but have difficulty simulating dynamic DML behavior in real-time under varying conditions due to their high complexity. Here, we introduce a data-driven deep learning method to model DMLs, aiming to achieve high accuracy with reduced computational complexity. This approach employs bidirectional long short-term memory (BiLSTM) enhanced by advanced feature recalibration and nonlinear fitting techniques.
View Article and Find Full Text PDFBMC Ecol Evol
January 2025
The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.
Background: In infected hosts, immune responses trigger a systemic energy reallocation away from energy storage and growth, to fuel a costly defense program. The exact energy costs of immune defense are however unknown in general. Life history theory predicts that such costs underpin trade-offs between host disease resistance and other fitness related traits, yet this has been seldom assessed.
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