Porcine epidemic diarrhea virus, a member of the family Coronaviridae, is an economically important pathogen that causes severe enteritis, vomiting, dehydration, and a high mortality rate, especially among suckling piglets. Here, we report the complete genome sequence (28,036 nucleotides [nt]) of a porcine epidemic diarrhea virus (PEDV) strain isolated in a novel outbreak in Shandong, China.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939784 | PMC |
| http://dx.doi.org/10.1128/genomeA.00619-16 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Characterization of a cell-adapted completely attenuated genotype GIIa porcine epidemic diarrhea virus strain.
Virology
January 2025
State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, 730046, China; Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou, 730046, China. Electronic address:
Porcine epidemic diarrhea virus (PEDV) has caused significant harm to the global pig industry since its discovery. In this study, a highly pathogenic strain of GIIa PEDV CH/HBXT/2018, isolated previously, was continuously passaged in Vero cells up to passage (P)240, resulting in a completely attenuated virus. The proliferation characteristics of different passages of the strain in Vero cells, pathogenicity in newborn piglets, and mutations in S gene sequence indicated that as the passage number increased, the replication efficiency of PEDV in Vero cells gradually improved, with a more pronounced cytopathic effect.
View Article and Find Full Text PDFMolecular Epidemiology and Genetic Evolution of Porcine Reproductive and Respiratory Syndrome Virus in Northern China During 2021-2023.
Viruses
January 2025
College of Veterinary Medicine, Hebei Agricultural University, Baoding 071000, China.
Porcine reproductive and respiratory syndrome virus (PRRSV), an important pathogen affecting the pig industry, is an RNA virus with high genetic diversity. In this study, 12,299 clinical samples were collected from northern China during 2021-2023 to investigate the molecular epidemiological characteristics and genetic evolution of PRRSV. All samples were screened using qRT-PCR and further analyzed through gene and whole-genome sequencing.
View Article and Find Full Text PDFComparative Adsorption of Porcine Reproductive and Respiratory Syndrome Virus Strains to Minnesota Soils.
Viruses
January 2025
Department of Veterinary Population Medicine, University of Minnesota, Saint Paul, MN 55108, USA.
Porcine reproductive and respiratory syndrome (PRRS) is an endemic disease affecting the swine industry. The disease is caused by the PRRS virus (PRRSV). Despite extensive biosecurity and control measures, the persistence and seasonality of the virus have raised questions about the virus's environmental dynamics during the fall season when the yearly epidemic onset begins and when crop harvesting and manure incorporation into the field occur.
View Article and Find Full Text PDFEffect of Fusion to the LTB Carrier Protein on Coronavirus Spike Protein Vaccine Candidates Produced in Maize.
Viruses
December 2024
Applied Biotechnology Institute, California Polytechnic Tech Park, San Luis Obispo, CA 93407, USA.
Coronaviruses continue to disrupt health and economic productivity worldwide. Porcine epidemic diarrhea virus (PEDV) is a devastating swine disease and SARS-CoV-2 is the latest coronavirus to infect the human population. Both viruses display a similar spike protein on the surface that is a target of vaccine development.
View Article and Find Full Text PDFPrevalence of spp. in Lithuanian Wild Boars ().
Pathogens
January 2025
Dr. L. Kriaučeliūnas Small Animal Clinic, Faculty of Veterinary, Veterinary Academy, Lithuanian University of Health Sciences, 47181 Kaunas, Lithuania.
is a bacteria responsible for a widespread zoonosis that affects both humans and animals. Leptospirosis is a challenging pathology to diagnose and treat since its signs are unspecific and symptoms vary greatly. The disease seems to be highly prevalent in environments where reservoir animals such as rats and small mammals are common.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!