Poulsen et al (Reports, 12 June 2015, p. 1238) argued that lower atmospheric oxygen levels during the Phanerozoic would have given a warmer climate. However, radiative and atmospheric structure changes under lower pressure both cause cooling, making their result unusual in that a hierarchy of models gives opposing results. Scrutiny of how radiative and cloud processes were represented, and a mechanistic explanation of the results, are required.
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http://dx.doi.org/10.1126/science.aad6976 | DOI Listing |
Nat Commun
January 2025
Frontiers Science Center for Molecular Design Breeding, Beijing Key Laboratory of Crop Genetic Improvement, College of Agronomy and Biotechnology, China Agricultural University, Beijing, China.
During cold acclimation in high-latitude and high-altitude regions, japonica rice develops enhanced cold tolerance, but the underlying genetic basis remains unclear. Here, we identify CTB5, a homeodomain-leucine zipper (HD-Zip) transcription factor that confers cold tolerance at the booting stage in japonica rice. Four natural variations in the promoter and coding regions enhance cold response and transcriptional regulatory activity, enabling the favorable CTB5 allele to improve cold tolerance.
View Article and Find Full Text PDFJ Colloid Interface Sci
April 2025
High Magnetic Field Laboratory, Hefei Institutes of Physical Science, Chinese Academy of Science, Hefei, Anhui 230031, PR China; University of Science and Technology of China, Hefei, Anhui 230026, PR China. Electronic address:
Synergistic therapy combining photothermal therapy (PTT) and chemodynamic therapy (CDT) has proven to be a highly effective strategy for cancer treatment. However, PTT heavily relies on the accumulation of therapeutic agents at the tumor site. The peroxidase (POD) activity of common catalysts can be rapidly exhausted during the accumulation process, prior to laser intervention, thereby diminishing the synergistic enhancement effect of the combined therapy.
View Article and Find Full Text PDFPathogens
December 2024
Department of Orthopaedics and Traumatology, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
Periprosthetic joint infections occur in 1-2% of all patients undergoing prosthetic joint surgeries. Although strong efforts have been made to reduce infection rates, conventional therapies like one- or two-stage revisions have failed to lower the infection rates. Cold atmospheric plasma (CAP) has shown promising results in reducing bacterial loads on surfaces.
View Article and Find Full Text PDFMolecules
January 2025
Graduate School of Biotechnology, Kyung Hee University, Yongin-si 17104, Republic of Korea.
The decline in autophagy disrupts homeostasis in skin cells, leading to oxidative stress, energy deficiency, and inflammation-all key contributors to skin photoaging. Consequently, activating autophagy has become a focal strategy for delaying skin photoaging. Natural plants are rich in functional molecules and widely used in the development of anti-photoaging cosmetics.
View Article and Find Full Text PDFLife (Basel)
January 2025
Department of Biology, University of Crete, Voutes University Campus, GR-70013 Heraklion, Crete, Greece.
This study investigates the resilience of the unicellular green microalga to extreme atmospheric conditions simulating those of Mars, Jupiter, and Titan. Using Earth as a control, experiments were conducted under autotrophic and mixotrophic conditions to evaluate the organism's photosynthetic efficiency, oxygen production, and biomass growth over 2, 5, and 12 days. Photosynthetic performance was analyzed through chlorophyll a fluorescence induction (JIP-test), metabolic activity via gas chromatography, and biomass accumulation measurements.
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