RF Ablation of Giant Hemangiomas Inducing Acute Renal Failure: A Report of Two Cases.

Cardiovasc Intervent Radiol

Departments of Radiology and Nuclear Medicine, VU University Medical Center, De Boelelaan 1117, 1081HV, Amsterdam, The Netherlands.

Published: November 2016

Objective: In patients that require treatment for hepatic giant cavernous hemangiomas (GCH), radiofrequency ablation (RFA) has been suggested to represent a safe and effective alternative to invasive surgery. In a recent report of bipolar RFA, using two expandable needle electrodes, was uneventfully performed in patients with large GCH (>10 cm). The objective of this report is to present two cases in which bipolar RFA of symptomatic GCH was complicated by acute kidney injury.

Materials And Methods: In 2015 we treated two patients for very large symptomatic GCH (15.7 and 25.0 cm) with bipolar RFA during open laparotomy.

Results: In both patients the urine showed a red-brown discoloration directly after the ablation. They became anuric and presented with progressive dyspnea, tachypnea, and tachycardia, requiring hemodialysis for a period of 1 month in one case. Lab results revealed hemepigment-induced acute kidney. Both patients fully recovered and both showed a complete relief of symptoms at 3 months following the procedure.

Conclusion: RFA for large GCHs can cause hemepigment-induced acute kidney injury due to massive intravascular hemolysis. The presented cases suggest that caution is warranted and advocate an upper limit regarding the volume of GCHs that can be safely ablated.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052325PMC
http://dx.doi.org/10.1007/s00270-016-1415-1DOI Listing

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