Onychomatricoma is a rare benign fibroepithelial filamentous tumor originating from the nail matrix. It typically presents with the clinical tetrad of xanthonychia, pachyonychia, proximal splinter hemorrhages and increased transverse overcurvature of the nail plate. The giant variant can easily confuse the clinician due to its extensive nail dystrophy that can mask the characteristic features of this tumor. Benign (fibrokeratoma, ungual fibroma, onycholytic matricoma) and malignant entities (Bowen's disease, squamous cell carcinoma, onycholytic carcinoma) are mimics of the disease. Nail surgery can facilitate the diagnosis, which should always be confirmed by histology, as rare variants do exist.
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http://dx.doi.org/10.1159/000445386 | DOI Listing |
Skin Appendage Disord
August 2018
Fredric Brandt Endowed Professor of Dermatology, University of Miami, Miami, FL, USA.
First described in 1992, onychomatricoma is a rare, benign, fibroepithelial tumor of the nail matrix with few reported cases in the literature. The tumor predominately affects the fingers of Caucasian women during the 5th decade of life and is typically slow growing and painless. The authors present a unique clinical presentation of a giant onychomatricoma in a darker-skinned 60-year-old South Asian individual who presented with a large dome-shaped nail that was smooth, shiny, and green.
View Article and Find Full Text PDFSkin Appendage Disord
May 2016
Nail Disorders Unit, Second Department of Dermatology, Attikon University Hospital, Athens, Greece.
Onychomatricoma is a rare benign fibroepithelial filamentous tumor originating from the nail matrix. It typically presents with the clinical tetrad of xanthonychia, pachyonychia, proximal splinter hemorrhages and increased transverse overcurvature of the nail plate. The giant variant can easily confuse the clinician due to its extensive nail dystrophy that can mask the characteristic features of this tumor.
View Article and Find Full Text PDFIndian J Dermatol
November 2015
Department of Dermatology, Sri Manakula Vinayagar Medical college and hospital, Kalitheerthalkuppam, Madagadipet, Pondicherry, India.
Giant onychomatricoma is a rare fibroepithelial nail matrix tumor with only two previous reports in literature, from Mexico. An 80-year-old female patient presented with a progressively painless mass in the left great toe nail, following trauma, of 2 years duration. On examination there was a single, hard, immobile mass of size 4 × 3 × 2 cm with proximal hyperpigmentation of the left great toe nail.
View Article and Find Full Text PDFJ Eur Acad Dermatol Venereol
March 2016
Dermatologic Surgery and Oncology Department, Hospital General de México "Dr. Eduardo Liceaga", Mexico City, Mexico.
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