AI Article Synopsis
- This study aimed to compare the antibacterial effectiveness of Myrrh, Neem, and Liquorice against E. faecalis, using 2% Chlorhexidine as a control, employing Real Time PCR technology.
- Fifty teeth were inoculated with E. faecalis and divided into five groups, each receiving different treatments over 21 days, with PCR assessing the microbial load after five days of treatment.
- Results indicated that Myrrh had antibacterial activity comparable to 2% CHX, while Neem and Liquorice followed in effectiveness, and saline showed no antibacterial properties.
Article Abstract
Aim: To compare the antibacterial efficacy of Azadirachta indica (Neem), Commiphora myrrha (Myrrh), Glycyrrhiza glabra (Liquorice) with 2% Chlorhexidine (CHX) against E. faecalis by using Real Time PCR.
Materials And Methods: A total of fifty teeth specimens (n=50) were inoculated with E. faecalis for 21 days. Specimens were divided into five groups (Group 1: Myrrh, Group 2: Neem, Group 3: Liquorice, Group 4: 2% CHX and Group 5: Saline (negative control)). The intracanal medicaments were packed inside the tooth. After 5 days, the remaining microbial load was determined by using real time PCR.
Results: Threshold cycle (Ct) values of Myrrh extract, Neem extract, Liquorice Extract, 2% CHX and saline were found to be 30.94, 23.85, 21.38, 30.93 and 17.8 respectively.
Conclusion: Myrrh extract showed inhibition of E.faecalis equal to that of 2% CHX followed by Neem, Liquorice and Saline.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911734 | PMC |
| http://dx.doi.org/10.2174/1874210601610010160 | DOI Listing |
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