This work was carried out to study the genotoxicity of pyridine in vitro on human leucocyte culture. Cyclophosphamide, a well-known carcinogen was used as positive control. The four different concentrations of pyridine and cyclophosphamide showed breaks and pulverization of chromosomes in dose dependent manner. Higher number of pulverization was observed with higher concentration of pyridine (3.25μg/mL). Based on this data, our results confirm that both pyridine and its precursor showed genotoxicity against human lymphocytes.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
genotoxicity pyridine
8
human lymphocytes
8
pyridine
5
vitro genotoxicity
4
pyridine human
4
lymphocytes work
4
work carried
4
carried study
4
study genotoxicity
4
pyridine vitro
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!