Background: Low-dose ropivacaine combined with intrathecal fentanyl can provide adequate anaesthesia with minimal haemodynamic variation. Preemptive analgesia can enhance analgesic effect of spinal anaesthesia without obvious side effects.
Aims: To assess the efficacy of preoperative intravenous oxycodone on transurethral resection of prostate (TURP) under 10 mg ropivacaine spinal anaesthesia combined with intrathecal 25 pg fentanyl.
Methods: Sixty patients undergoing TURP were randomly divided into two groups: Group o (n=30), in which the patients were administered 0.1 mg.kg-1 oxycodone intravenously 10 min prior to the operation for 2 min, and Group C (n=30) in which the patients were administered intravenously a similar volume of 0.9% saline. The participants were injected with hyperbaric 10 mg ropivacaine and 25 µg fentanyl intrathecally. The block characteristics, hemodynamic values, the tramadol consumption and adverse effects were analyzed.
Results: The peak level of sensory block was lower in Group C. Time to the first analgesic request and time to two-segment regression of sensory block were shorter in Group C. Fewer patients in Group 0 were given postoperative analgesics.
Conclusion: Preoperative intravenous oxycodone can prolong analgesic effect of this method and postoperative analgesia.
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