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Long-Standing Remission After Tildrakizumab Treatment in a Case of Refractory Type I Pityriasis Rubra Pilaris in a Breast Cancer Patient.
Clin Cosmet Investig Dermatol
October 2024
Dermatology Unit, Azienda Unità Sanitaria Locale- IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Pityriasis rubra pilaris (PRP) is a rare chronic inflammatory skin disease characterised by follicular keratotic papules and perifollicular erythema coalescing into orange-red scaly plaques, and palmoplantar keratoderma. Characteristic islands of sparing are usually observed. A standardised therapeutic approach is lacking owing to the infrequent occurrence of this disease.
View Article and Find Full Text PDFA Snapshot of Biomarkers in Psoriasis.
Curr Drug Discov Technol
November 2024
Clinical Research and Pharmacovigilance, Serum Institute of India Pvt. Ltd., Hadapsar, Pune, India.
A persistent long-standing, inflammatory skin condition that is brought on by a variety of factors is psoriasis. It is distinguished by itchy, scaly, reddish plaques, particularly on areas of the body that are frequently chafed, including the extensor sites of the limbs. Recent developments in molecular-targeted therapy that use biologics or small-molecule inhibitors can effectively cure even the worst psoriatic indications.
View Article and Find Full Text PDFAdnexotropic and granulomatous mycosis fungoides following TNF-α inhibitor treatment.
J Cutan Pathol
July 2023
Dartmouth Geisel School of Medicine, Hanover, New Hampshire, USA.
Article Synopsis
- The case presented involves a patient who developed mycosis fungoides (MF), a type of CTCL, after starting adalimumab, showcasing unique pathological results from skin biopsies of different affected areas.
- The findings suggest that TNF-α inhibitors may obscure typical signs of MF, making it vital for healthcare providers to recognize this risk and consider pre-existing conditions when treating patients.
Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma (CTCL). It may arise rapidly in a scar or keloid, presumably due to a long-standing proliferative state or autoimmune theory. There should be a low threshold for performing a skin biopsy if unusual lesions develop at those sites.
View Article and Find Full Text PDFGiant Bowen's Disease on the Face: Case Report and Review of the Literature.
Open Access Maced J Med Sci
February 2019
University Clinic of Dermatology, Ss. Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia.
Background: Giant Bowen's disease is a rare and unusual clinical manifestation. Presenting as extensive scaly erythematous patch or plaque, it gives rise to a wide spectrum of dermatological differential diagnoses.
Case Presentation: We report a patient with giant Bowen's disease on the face that was successfully treated with topical 5 % imiquimod.
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