Background: The anterior region of the mandible is generally considered to be a safe region to invasive procedures; however, on its internal face, uncountable penetrating canals may be encountered.
Objective: To perform morphometrical and topographical analysis of endosseous canals located at the inner side of the mandibular anterior region, using cone-beam computed tomography.
Methods: Forty-six examinations were digitally analyzed. Localization of canals in relation to the midline, trajectories, communications between other anatomic structures and relation with teeth were evaluated. Longitudinal and transversal diameters of the canals and distances to the lower edge and symphysis of the mandible were also measured.
Results: All individuals had at least 1 canal, with a mean of 2.3 and higher prevalence in the midline region. The adjacent teeth to the canals were usually the incisors but the authors could not determine the connected anatomical structure in most patients. Both the mean diameters were quite similar, about 1 mm; however, the trajectories and distances to the lower edge and symphysis of mandible showed a remarkable heterogeneity among the individuals.
Conclusions: These endosseous canals are consistent and clinically relevant findings and should never be underestimated by professionals.
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http://dx.doi.org/10.1097/SCS.0000000000002783 | DOI Listing |
Ocul Immunol Inflamm
January 2025
Departamento de Inmunología, Oftalmología y ORL, Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain.
Purpose: HLA-G is a non-classical HLA class I gene encoding a molecule endowed with immunomodulatory properties, playing important immunosuppressive and tolerogenic roles in immuno-privileged organs. Fluctuations in its expression levels have been correlated with the predisposition to autoinflammatory disorders, notably uveitis, characterized by inflammation of the uvea. In the present work, DNA was obtained from saliva samples of 147 Spanish patients with uveitis, with subsequent analysis focusing on the distribution of polymorphisms within the 3'UTR region of the gene (a region known to modulate the expression of the HLA-G molecule).
View Article and Find Full Text PDFHum Brain Mapp
February 2025
Department of Neurology, Centre for Leading Medicine and Advanced Technologies of IHM, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Apathy is a common neuropsychiatric symptom following stroke, characterized by reduced goal-directed behavior. The reward decision network (RDN), which plays a crucial role in regulating goal-directed behaviors, is closely associated with apathy. However, the relationship between poststroke apathy (PSA) and RDN dysfunction remains unclear due to apathy heterogeneity, the confounding effect of depression and individual variability in lesion impacts.
View Article and Find Full Text PDFClin Oral Implants Res
January 2025
Department of Oral and Maxillofacial Surgery-Plastic Operations, University Medical Center Mainz, Mainz, Germany.
Objectives: This experimental study compared the accuracy of implant insertion using the free-hand (FH) technique, static computer-aided surgery (S-CAIS), or dynamic computer-assisted surgery (D-CAIS) and to evaluate the correlation of learning curves between surgeons' experience and surgical time.
Materials And Methods: Thirty-six models were randomly assigned to three groups (FH, n = 12; S-CAIS, n = 12; D-CAIS, n = 12). Each model was planned to receive four implants in the maxillary anterior and posterior regions.
Addict Biol
January 2025
Department of Neurosurgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Morphine dependence or addiction is a serious global public health and social problem, and traditional treatments are very limited. Deep brain stimulation (DBS) has emerged as a new potential treatment for drug addiction. Repeated use of morphine leads to neuroadaptive and molecular changes in the addiction-related brain regions.
View Article and Find Full Text PDFCleft Palate Craniofac J
January 2025
Section of Oral and Maxillofacial Surgery, Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, Brazil.
Objective: To investigate and compare the morphology of the sphenoid sinus (SS) in patients with bilateral cleft lip and palate (BCLP) and the control group.
Design: A retrospective comparative study.
Setting: Craniofacial rehabilitation institution.
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