Purpose: To describe the formation of a retinal pigment epithelial (RPE) tear following immunosuppressive treatment of a large choroidal granuloma in a patient with sarcoidosis-related panuveitis.

Methods: A 25-year-old woman presented with bilateral sarcoidosis-related panuveitis and optic disc edema in both eyes with a large choroidal granuloma temporal to the fovea in the left eye. High-dose oral prednisone therapy was given.

Results: High-dose oral prednisone therapy produced improvement in her panuveitis with reduction in size of the left choroidal granuloma. An RPE tear overlying the flattening choroidal granuloma developed by 3 weeks of treatment.

Conclusions: Treatment of choroidal granuloma with rapid reduction in size may result in an RPE tear.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071675PMC
http://dx.doi.org/10.1080/09273948.2016.1180402DOI Listing

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