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Choroidal metastases from thoracic cancer: a retrospective study on clinical characteristics and treatment efficacy.
Front Med (Lausanne)
February 2025
Center of Optometry, Department of Ophthalmology, Peking University People's Hospital, Institute of Ophthalmic and Optometric Medicine, Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Optometry School of Peking University Health Science Center, Beijing, China.
Objective: This study aimed to examine the clinical characteristics of choroidal metastases (CMs) and assess the efficacy of various treatment strategies for CMs in a specific patient cohort.
Methods: This retrospective case series study included 32 patients (38 eyes) diagnosed with CM at the Department of Ophthalmology, Peking University People's Hospital, between 2009 and 2022. The cohort included 10 male patients (10 eyes) and 22 female patients (28 eyes), with a mean age of 52.
[A case of multifocal glioblastoma with ring enhancement, mimicking cerebral toxoplasmosis with ring-enhanced lesions].
Rinsho Shinkeigaku
February 2025
Department of Neurology, Kakogawa Central City Hospital.
A 57-year-old male patient with a history of daily contact with stray cats was transferred to our hospital with weakness in the left limb and mild disturbance of consciousness. At presentation, he had no fever or signs of meningeal irritation. Cerebrospinal fluid examination revealed lymphocytic pleocytosis; however, the cerebrospinal culture was negative.
View Article and Find Full Text PDFAssociation between Cystic Fibrosis and Pericardial Calcification Detected at Chest CT in Adults.
Radiology
February 2025
Department of Medical Imaging, St Michael's Hospital, University of Toronto, 30 Bond St, Toronto, ON, Canada M5B 1W8.
Background Although pericardial calcification has been observed on chest CT scans in patients with cystic fibrosis (CF), its prevalence and characteristics have not been elucidated. Purpose To determine the prevalence and characteristics of pericardial calcification, and identify clinical variables associated with it, in adult patients with CF and to compare this prevalence with that in individuals without CF. Materials and Methods This was a retrospective, single-center case-control study including consecutive patients with CF who underwent chest CT between January 2021 and December 2022.
View Article and Find Full Text PDFSudden cardiac death associated with severe atherosclerosis in a young dog.
J Vet Cardiol
January 2025
James Specialist Veterinary Cardiology, Mill Run, Twemlow Lane, Cranage, CW4 8EX, United Kingdom.
A two-year-old female neutered wirehaired Dachshund presented with a four-week history of progressive intermittent pelvic limb weakness, pain and collapse episodes. Serum biochemistry revealed moderate hypercholesterolaemia and hypertriglyceridemia. Electrolytes and haematology were unremarkable.
View Article and Find Full Text PDFQuantifying cell divisions along evolutionary lineages in cancer.
Nat Genet
March 2025
Department of Genetics, Harvard Medical School, Boston, MA, USA.
Cell division drives somatic evolution but is challenging to quantify. We developed a framework to count cell divisions with DNA replication-related mutations in polyguanine homopolymers. Analyzing 505 samples from 37 patients, we studied the milestones of colorectal cancer evolution.
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