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Abnormal Venous Flow in Pregnant Women with Mild Right Ventricular Dysfunction in Repaired Tetralogy of Fallot: A Clinical Model for Organ Dysfunction in Preeclampsia.
J Clin Med
December 2024
Department of Cardiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Pregnant women with congenital heart disease carry a high risk of complications, especially when cardiac function is suboptimal. Increasing evidence suggests that impaired right ventricular (RV) function has a negative effect on placental function, possibly through venous congestion. We report a case series of hepatic and renal venous flow patterns in pregnant women with right ventricular dysfunction after repaired Tetralogy of Fallot (ToF), relative to those observed in normal pregnancy and preeclampsia.
View Article and Find Full Text PDFPaediatric renal tumours: an update on challenges and recent developments.
Virchows Arch
January 2025
Histology Laboratory, Children's Health Ireland, Dublin, Ireland.
Paediatric renal tumours include a broad range of neoplasms which largely differ, but also overlap to a smaller extent, with adult kidney cancer. These include the embryonal tumour nephroblastoma, which accounts for the majority of cases of kidney cancer in the first decade of life and, despite boasting a cure in ~ 90% cases, still presents clinical challenges in a small proportion of cases. A variety of less common mesenchymal tumours, including the mostly indolent congenital mesoblastic nephroma, clear cell sarcoma of kidney which continues to be associated with poor outcomes for higher stage disease, and the typically lethal malignant rhabdoid tumour, form the bulk of the remaining presentations in the first decade.
View Article and Find Full Text PDFTranscription Factor: Key Regulator in Renal Physiology and Pathogenesis.
Int J Mol Sci
October 2024
Group of Genetics and Developmental Biology of Renal Disease, Laboratory of Nephrology, No. 11, Health Research Institute of Santiago de Compostela (IDIS), Clinical University Hospital (CHUS), 15706 Santiago de Compostela, Spain.
Article Synopsis
- * Mutations in this gene can disrupt normal function, resulting in renal issues like polycystic kidney disease and structural kidney abnormalities, as well as extrarenal problems like diabetes, genitourinary malformations, and neurodevelopmental disorders.
- * Future research aims to clarify how these genetic changes affect health, which could improve clinical management and support for affected patients and their families.
A case of hydronephrosis due to intrarenal ureteral obstruction in a Japanese Black calf.
J Vet Med Sci
November 2024
Vetsuisse Faculty, Clinic for Ruminants, University of Bern, Bern, Switzerland.
A 23-day-old Japanese Black female calf presented with distension of the lower abdomen. Abdominal ultrasonography revealed a cystic structure with fluid accumulation and moderate echoluminance in the right abdominal cavity. Ultrasonography and contrast-enhanced computed tomography revealed congenital hydronephrosis due to narrowing of the intrarenal ureter, and right kidney resection was performed.
View Article and Find Full Text PDFImaging of Perirenal and Intrarenal Lymphatic Vessels: Anatomy-based Approach.
Radiographics
March 2024
From the Department of Radiology (H.T., A.I., T.A.P., N.T.) and Department of Medicine, Division of Rheumatology (Y.S.), Mayo Clinic, 200 First St SW, Rochester, MN 55905; Department of Radiology, Okayama City Hospital, Okayama, Japan (T.T.); Department of Radiology, Jichi Medical University, Tochigi, Japan (S.M.); Department of Diagnostic and Interventional Radiology, University of Tsukuba, Ibaraki, Japan (M.M.); and Department of Radiology, Mayo Clinic, Scottsdale, Ariz (A.K.).
Article Synopsis
- The lymphatic system includes lymphoid organs and vessels, but findings related to intrarenal and perirenal lymphatic vessels are not well-documented in radiology.
- Lymphatic pathways in the renal cortex allow lymph to travel towards the hilum and capsular plexus, which can be visualized through contrast medium during CT urography, indicating possible complications like pyelolymphatic backflow.
- Conditions like congenital renal lymphangiectasia and acquired renal complications can affect imaging post-kidney transplant, with distinct fluid patterns in the urinary tract indicating issues like chyluria, highlighting the importance of understanding lymphatic pathways for effective cancer management.
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