In the title compound {systematic name: 4,4'-[1,1'-(hydrazinediyl-idene)bis-(ethan-1-yl-1-yl-idene)]bis-(benzene-1,3-diol)}, C16H16N2O4·2C3H7NO, the (E,E)-2',4'-di-hydroxy-aceto-phenone azine mol-ecule is centrosymmetric, the mid-point of the N-N bond being located on an inversion centre. All the non-H atoms of the azine mol-ecule are approximately coplanar, the maximum deviation being 0.017 (2) Å. An intra-molecular O-H⋯N hydrogen bond occurs between the azine N atom and the hy-droxy group. In the crystal, azine and di-methyl-formamide solvent mol-ecules are linked by O-H⋯O hydrogen bonds.
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http://dx.doi.org/10.1107/S2056989016003686 | DOI Listing |
Chem Sci
January 2025
Engineering of Molecular NanoSystems, Université libre de Bruxelles (ULB) Avenue F.D. Roosevelt 50, CP165/64 B-1050 Brussels Belgium
Stimuli-responsive transmembrane ion transport has become a prominent area of research due to its fundamental importance in cellular processes and potential therapeutic applications. Commonly used stimuli include pH, light, and reduction or oxidation agents. This paper presents the use of dynamic covalent chemistry to activate and modulate the transmembrane transport of chloride in liposomes.
View Article and Find Full Text PDFMini Rev Med Chem
January 2025
Department of Chemistry, Abdul Wali Khan University, Mardan, 23200, Pakistan.
Organic compounds containing azines, di-imines, or bis-Schiff-bases have two azomethine (-CH=N-) functional groups associated with a bridging component. These constituents have attracted attention from a diversity of disciplines, comprising coordination, medicinal, agriculture chemistry, and organic synthesis, because of their comprehensive chemical reactivity and nature. This study determines common synthetic approaches and various biological and pharmacological activities of several substituted bis-Schiff byproducts.
View Article and Find Full Text PDFJ Hazard Mater
January 2025
Department of Chemistry, National Institute of Technology Calicut, Kerala 673601, India. Electronic address:
Hydrazine (NH) and hydrogen sulfide (HS) are environmental contaminants that adversely affect human health. Fluorescence-based detection methods for these analytes utilize their nucleophilicity and reducing ability. Therefore, fluorescent sensors capable of detecting and distinguishing hydrazine and HS are highly beneficial.
View Article and Find Full Text PDFChemistry
January 2025
Florida State University, Chemistry and Biochemistry, 95 Chieftan Way, 32306, Tallahassee, UNITED STATES OF AMERICA.
Since antiquity, alkaloid natural products have served as medicinal ingredients that still contribute as an inspiration for the development of novel therapeutics. For the synthetic chemist, much of the importance of natural products lies in their acting as a forcing-function for the invention of new synthetic strategies and tactics for molecular assembly. With this rich history in mind, it remains an important goal for chemists to build nitrogenous structures with greater efficiency, abiding by economies of synthesis.
View Article and Find Full Text PDFTop Curr Chem (Cham)
December 2024
Department of Chemistry, King Khalid University, P.O. Box 9004, 61413, Abha, Saudi Arabia.
Carbazoles are nitrogen-containing aromatic heterocycles, having widespread applications in the field of photovoltaics. Carbazole-based photosensitizers have tunable features for absorption on semi-conductor (tellurium dioxide or zinc oxide) layers to create sufficient push-pull force in the conversion of sunlight into electrical energy, thus presenting as promising heterocyclic donor candidates to be used in dye-sensitized solar cells. For the synthesis of these dyes, various structural designs are available, namely, D-A, D-π-A, D-D-π-A, D-A-π-A, A-π-D-π-A-π-A, and D2-π-A that all involve incorporating carbazole as a donor (D), along with spacer (π-extender) moieties, such as thiophene, phenol, ethynylene, nitromethane, azine, thiadiazole, or acetonitrile.
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