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Negotiating a physically active life in tune with ageing: a grounded theory study of older persons' experiences of participating in high-intensity interval training.
BMC Geriatr
January 2025
Community Medicine and Rehabilitation, Physiotherapy, Umeå University, Umeå, Sweden.
Background: Physical activity and exercise are promoted worldwide as effective interventions for healthy ageing. Various exercise initiatives have been developed and evaluated for their efficacy and effectiveness among older populations. However, a deeper understanding of participants' experiences with these initiatives is crucial to foster long-term activity and exercise among older persons.
View Article and Find Full Text PDFTime evolution of a pumped molecular magnet-A time-resolved inelastic neutron scattering study.
Proc Natl Acad Sci U S A
January 2025
William H. Miller III Department of Physics and Astronomy, The Johns Hopkins University, Baltimore, MD 21218.
Introducing an experimental technique of time-resolved inelastic neutron scattering (TRINS), we explore the time-dependent effects of resonant pulsed microwaves on the molecular magnet CrFPiv. The octagonal rings of magnetic Cr atoms with antiferromagnetic interactions form a singlet ground state with a weakly split triplet of excitations at 0.8 meV.
View Article and Find Full Text PDFEvaluating the effectiveness of oral HIV self testing according to distribution models in Cameroon.
Sci Rep
December 2024
Division of Health Operational Research, Ministry of Public Health, Yaoundé, Cameroon.
Innovative strategies such as HIV self-testing (HIVST) are useful for identifying hard-to-reach people living with HIV/AIDS (PLHIV), especially in developing settings where considerable gaps still exist in reaching the first 95% UNAIDS target. We evaluated the effectiveness of HIVST in Cameroon using several distribution models and investigated the predictors of HIV seropositivity among self-testers. The study was conducted from 2021 to 2022 in three regions in Cameroon.
View Article and Find Full Text PDFRational design of uniform SiO-based afterglow microparticles for photonic crystals.
Mater Horiz
December 2024
Frontiers Science Center for Flexible Electronics (FSCFE), MIIT Key Laboratory of Flexible Electronics (KLoFE), Shaanxi Key Laboratory of Flexible Electronics, Xi'an Key Laboratory of Flexible Electronics, Xi'an Key Laboratory of Biomedical Materials & Engineering, Xi'an Institute of Flexible Electronics, Institute of Flexible Electronics (IFE), Northwestern Polytechnical University, Xi'an 710072, Shaanxi, China.
Despite recent advancements in organic phosphors, the synthesis of monodisperse afterglow microparticles (MPs) suitable for creating photonic crystals remains challenging. The SiO matrix is an attractive host material for activating the long-lived emissions of doped molecules due to several factors, including its cross-linked polymer-like structure, abundance of -OH groups, robustness, and presence of numerous emitter defects. However, the Stöber method struggles to produce monodisperse molecule-doped SiO MPs due to the complexity of the system.
View Article and Find Full Text PDFDiagnostic and Therapeutic Microbial Circuit with Application to Intestinal Inflammation.
ACS Synth Biol
December 2024
Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125, United States.
Bacteria genetically engineered to execute defined therapeutic and diagnostic functions in physiological settings can be applied to colonize the human microbiome, providing in situ surveillance and conditional disease modulation. However, many engineered microbes can only respond to single-input environmental factors, limiting their tunability, precision, and effectiveness as living diagnostic and therapeutic systems. For engineering microbes to improve complex chronic disorders such as inflammatory bowel disease, the bacteria must respond to combinations of stimuli in the proper context and time.
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