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Development and validation of a sport-specific shoulder score questionnaire for functional fitness and weightlifting athletes.
J Sports Med Phys Fitness
January 2025
Department of Orthopedics and Trauma Surgery, BG University Hospital, Bochum, Germany.
Background: So-called scores are a frequently used evaluation system in clinical examinations to assess the function or limitations of a joint such as the shoulder. However, research indicates that these general scores often have limited validity for specific patient groups, such as athletes. Known as a demanding patient population, athletes have unique needs.
View Article and Find Full Text PDFEnergy availability and macronutrient intake over a 7-day training period in adolescent rugby players.
J Sports Med Phys Fitness
January 2025
Research Unit on Youth, Physical Activity, Sports and Health (J-AP2S), University of Toulon, Toulon, France.
Background: Understanding the dietary intake of elite adolescent athletes and its adequacy with sport nutrition recommendation is a key issue for health and player development, as well as performance and recovery. Energy availability needs to be considered to ensure optimal health and performance in young athletes. The present study aimed to quantify energy availability, energy expenditure and macronutrient intake in young male rugby union players competing at national level.
View Article and Find Full Text PDFTransplant 101: Helping Patients Navigate the Complexity of the Kidney Transplant Waitlist.
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Kidney Transplant Coordinator, Atrium Health, Carolinas Medical Center in Charlotte, NC.
Patients in need of a kidney transplant have the option of receiving a kidney from a living donor or a deceased donor. Patients in the United States who do not have an available living donor typically wait on the deceased donor waiting list for an average of three to five years, although some patients may wait longer. The waiting list is very complex and intended to allocate kidneys in a fair and equitable manner.
View Article and Find Full Text PDFThrombotic Microangiopathy Associated with Systemic Adeno-Associated Virus Gene Transfer: Review of Reported Cases.
Hum Gene Ther
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BridgeBio Gene Therapy, Palo Alto, California, USA.
Complement-mediated thrombotic microangiopathy (TMA) in the form of atypical hemolytic uremic syndrome (aHUS) has emerged as an immune complication of systemic adeno-associated virus (AAV) gene transfer that was unforeseen based on nonclinical studies. Understanding this phenomenon in the clinical setting has been limited by incomplete data and a lack of uniform diagnostic and reporting criteria. While apparently rare based on available information, AAV-associated TMA/aHUS can pose a substantial risk to patients including one published fatality.
View Article and Find Full Text PDFPEGylated Granulocyte Colony-Stimulating Factor and Plerixafor Enhance Autologous Stem and Progenitor Cell Mobilization and Transplantation in Pediatric Patients.
Stem Cells Dev
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Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Autologous hematopoietic stem cell transplantation is used to restore bone marrow function after high-dose chemotherapy. For apheresis, granulocyte colony-stimulating factor (G-CSF) is standard of care, but obtaining sufficient stem cells can be challenging. Other mobilization agents include plerixafor and PEGylated G-CSF (PEG-G-CSF).
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