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Influences of pulsed electric field parameters on cell electroporation and electrofusion events: Comprehensive understanding by experiments and molecular dynamics simulations.
PLoS One
January 2025
Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou, China.
Electroporation and electrofusion are efficient methods, which have been widely used in different areas of biotechnology and medicine. Pulse strength and width, as an external condition, play an important role in the process of these methods. However, comparatively little work has been done to explore the effects of pulsed electric field parameters on electroporation and electrofusion.
View Article and Find Full Text PDFTracking and Navigation Technologies for Image-Guided Trans-Arterial Interventions.
Tech Vasc Interv Radiol
December 2024
Department of Radiology, Mayo Clinic, Phoenix, AZ. Electronic address:
Trans-arterial interventions are an increasingly utilized approach for diagnosing and treating a wide range of pathologies, providing superior patient outcomes compared to traditional open surgical methods. Recent advancements in tracking and navigation technologies have significantly refined these interventions, enhancing procedural precision and success. Advanced imaging modalities, such as fluoroscopy, cone beam computed tomography (CBCT), and intravascular ultrasound (IVUS), are frequently used strategies offering critical real-time guidance.
View Article and Find Full Text PDFElectromagnetic navigation guided tailored lamino-pedicular intralesional marginal resection of recurrent sacral osteoblastoma: a case report.
J Spine Surg
December 2024
Department of Orthopaedic Surgery, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Background: Electromagnetic navigation (EMN) is an advanced technology increasingly utilized in orthopedic surgery for its ability to provide real-time intraoperative guidance. Its application in spinal surgery is evolving rapidly, particularly for complex cases like tumor lesions. Spinal osteoblastomas, characterized by their benign nature, primarily affect the posterior elements of the spine.
View Article and Find Full Text PDFRecommendations for the Safe Application of Temporal Interference Stimulation in the Human Brain Part II: Biophysics, Dosimetry, and Safety Recommendations.
Bioelectromagnetics
January 2025
Foundation for Research on Information Technologies in Society, Zurich, Switzerland.
Temporal interference stimulation (TIS) is a new form of transcranial electrical stimulation (tES) that has been proposed as a method for targeted, noninvasive stimulation of deep brain structures. While TIS holds promise for a variety of clinical and nonclinical applications, little data is yet available regarding its effects in humans and its mechanisms of action. To inform the design and safe conduct of experiments involving TIS, researchers require quantitative guidance regarding safe exposure limits and other safety considerations.
View Article and Find Full Text PDFBackground Light Suppression for Multispectral Imaging in Surgical Settings.
Sensors (Basel)
December 2024
Institute of Smart Systems and Services, Pforzheim University, 75175 Pforzheim, Germany.
Multispectral imaging (MSI) enables non-invasive tissue differentiation based on spectral characteristics and has shown great potential as a tool for surgical guidance. However, adapting MSI to open surgeries is challenging. Systems that rely on light sources present in the operating room experience limitations due to frequent lighting changes, which distort the spectral data and require countermeasures such as disruptive recalibrations.
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