This paper presented a discussion of the initial appearance and atypical clinical course, histopathology, treatment, and prognosis of a case of extraskeletal myxoid chondrosarcoma that originated on the plantar surface of the left foot and that metastasized to the mandible. The clinical behavior of this neoplasm, as reported, is distinctively less aggressive and therefore thought to have a better prognosis than chondrosarcoma of bone. Contrary to the biologic behavior reported in the literature, however, our patient had a less than six-year remission from the neoplasm.
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Non-myxoid solid variant of extraskeletal myxoid chondrosarcoma: An underrecognized subtype.
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Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, 30322, USA. Electronic address:
Introduction: Extraskeletal myxoid chondrosarcoma (EMC) is a rare sarcoma defined by NR4A3 gene rearrangements, typically featuring uniform cells with eosinophilic cytoplasm and mild atypia, arranged in cords or clusters within a chondromyxoid stroma. A cellular variant, characterized by increased cellular density and a solid growth pattern, has been recognized.
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View Article and Find Full Text PDFClinical, imaging and pathological features of extraskeletal myxoid chondrosarcoma.
Skeletal Radiol
September 2024
Division of Musculoskeletal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital, Yawkey 6E 55 Fruit Street, Boston, MA, 02114, USA.
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Department of Anatomic Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA.
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