Objective: Trauma patient requires a complex therapeutic management because of multiple severe injuries or secondary complications. The most significant injury found in patients with trauma is head injury, which has the greatest impact on mortality. Intracranial pressure (ICP) monitoring is required in severe traumatic head injury because it optimises treatment based on ICP values and cerebral perfusion pressure (CPP).
Methods: From a total of 64 patients admitted in the intensive care unit (ICU) 'Casa Austria', from the Polytraumatology Clinic of the Emergency County Hospital "Pius Brinzeu" Timisoara, Romania, between January 2014 and December 2014; only patients who underwent ICP monitoring (n=10) were analysed. The study population was divided into several categories depending on the time passed since trauma to the time of installation of ICP monitoring (<18 h, 19-24 h and >24 h). Comparisons were made in terms of the number of days admitted in the ICU and mortality between patients with head injury who benefited and those who did not benefit from ICP monitoring.
Results: The results show the positive influence of ICP monitoring on the number of admission days in ICU because of the possibility that the number of admission days to augment therapeutic effects in patients who benefited from ICP monitoring reduces by 1.93 days compared with those who did not undergo ICP monitoring.
Conclusion: ICP monitoring and optimizing therapy according to the ICP and CPP has significant influence on the rate of survival. ICP monitoring is necessary in all patients with head trauma injury according to recent guidelines. The main therapeutic goal in the management of the trauma patient with head injury is to minimize the destructive effects of the associated side effects.
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http://dx.doi.org/10.5152/TJAR.2015.56933 | DOI Listing |
Front Neurol
January 2025
Department of Ultrasound, The Second Affiliated Hospital of Shandong First Medical University, Tai'an, China.
Objective: Elevated intracranial pressure (ICP), a common complication in traumatic brain injuries (TBI), can lead to optic nerve sheath diameter (ONSD) enlargement and flow spectrum changes from the internal carotid artery (ICA) to middle cerebral artery (MCA). This study will investigate the use of Cervical-Cerebral Arterial Ultrasound (CCAU) for non-invasive ICP assessment and evaluating the related indices' clinical utility in TBI patients with decompressive craniotomy (DC).
Methods: ONSD and flow spectrum changes were measured within 24 h after DC in 106 patients via ultrasonic ONSD measurement and CCAU, simultaneously.
J Neuroophthalmol
January 2025
Department of Ophthalmology (JGJ-C, TE, Y-HC, LRD, RAG), Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts; Frank H. Netter Medical School (JGJ-C), North Haven, Connecticut; and Department of Anesthesiology (DZ), Critical Care and Pain Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
Background: Patients with craniosynostosis are at high risk of developing elevated intracranial pressure (ICP) causing papilledema and secondary optic atrophy. Diagnosing and monitoring optic neuropathy is challenging because of multiple causes of vision loss including exposure keratopathy, amblyopia, and cognitive delays that limit examination. Peripapillary hyperreflective ovoid mass-like structures (PHOMS) are an optical coherence tomography (OCT) finding reported in association with papilledema and optic neuropathy.
View Article and Find Full Text PDFBiol Trace Elem Res
January 2025
Department of Biology, Faculty of Science, Arak University, Arak, 384817758, Iran.
Contamination of aquatic ecosystems with heavy metals poses a significant global issue due to its hazardous effects and persistent accumulation in living organisms. This study analyzed 51 fish samples from two species of Black Fish, Capoeta saadii and Capoeta trutta, collected from Iran's Khorramroud River during the summer and fall of 2022 to assess heavy metal accumulation in their gill, liver, and muscle tissues. After biometry, the studied tissues of each fish were isolated to measure the concentration of heavy metals (cadmium (Cd), zinc (Zn), chromium (Cr), lead (Pb), copper (Cu), and nickel (Ni)).
View Article and Find Full Text PDFFood Addit Contam Part B Surveill
January 2025
College of Agricultural Engineering Science, Food Science and Quality Control Department, University of Sulaimani, Sulaimani, Iraq.
Potential toxic elements are substances that can accumulate in foodstuffs and pose risks to human health even at low levels, or when their levels exceed safety thresholds. A total of 78 breakfast cereals were purchased from the Kurdistan region, Iraq. Their PTE levels were analysed and associated health risks were calculated.
View Article and Find Full Text PDFCurr Environ Health Rep
January 2025
School of Health Sciences, Purdue University, West-Lafayette, IN, 47906, USA.
Purpose Of Review: This review explores the use of Inductively Coupled Plasma Mass Spectrometry (ICP-MS) and X-ray Fluorescence (XRF) for quantifying metals and metalloids in biological matrices such as hair, nails, blood, bone, and tissue. It provides a comprehensive overview of these methodologies, detailing their technological limitations, application scopes, and practical considerations for selection in both laboratory and field settings. By examining traditional and novel aspects of each method, this review aims to guide researchers and clinical practitioners in choosing the most suitable analytical tool based on their specific needs for sensitivity, precision, speed, and sample preparation.
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