Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898121PMC
http://dx.doi.org/10.4103/0976-3147.182773DOI Listing

Publication Analysis

Top Keywords

infantile desmoplastic
4
desmoplastic astrocytoma
4
astrocytoma magnetic
4
magnetic resonance
4
resonance imaging
4
imaging suggestive
4
suggestive pathology
4
infantile
1
astrocytoma
1
magnetic
1

Similar Publications

Here we present a co-occurrence of a non-typical presentation of DIG/DIA and multiple sclerosis in a 13-year-old female. Our case highlights how a thorough investigation prior to treatment is needed in patients with such condition to choose proper management for better prognosis.

View Article and Find Full Text PDF
Article Synopsis
  • NTRK gene fusions occur in about 1% of gliomas and are considered promising targets for treatment due to their ability to cross the blood-brain barrier, leading to interest in TRK inhibitors.
  • A study of 12 NGS-verified NTRK-fused gliomas at Seoul National University Hospital found that DLGGs mostly had only NTRK fusions, while DHGGs often had additional genetic mutations, with various fusion partners identified for NTRK1 and NTRK2.
  • Treatment outcomes using TRK inhibitors varied significantly; one child with DLGG showed stable disease, while a child with DHGG and an adult with glioblastoma experienced tumor recurrence and progression, highlighting the mixed
View Article and Find Full Text PDF
Article Synopsis
  • Low-grade gliomas are the most common brain tumors in children and adolescents, often leading to uncontrolled seizures when located in the temporal lobe.
  • A review of literature highlights various tumor types, surgical treatment options, and outcomes, indicating that complete resection of tumors is crucial for achieving favorable seizure outcomes.
  • Management of these conditions should involve a multidisciplinary team focused on epilepsy surgery, as early and effective intervention significantly improves patient survival and reduces seizure-related issues.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!