Aim: This study was aimed at identifying factors which may affect the gap length in cases of esophageal atresia with tracheoesophageal fistula (EA-TEF) and whether gap length plays any role in determining the outcome.
Materials And Methods: All consecutive cases of EA-TEF were included and different patient parameters were recorded. Plain radiographs with a nasogastric tube in the upper esophagus were taken. Patients were grouped into T1-T2; T2-T3; T3-T4; and T4 depending on the thoracic vertebral level of the arrest of the tube. During surgery, the gap length between the pouches was measured using a Vernier caliper and the patients were grouped into A, B, and C (gap length >2.1 cm; >1-≤2 cm and ≤1 cm). The operative gap groups were compared with the radiography groups and the other recorded parameters.
Results: Total numbers of cases were 69. Birth weight was found to be significantly lower in Group A (mean = 2.14 kg) as compared to Group B (mean = 2.38 kg) and Group C patients (mean = 2.49 kg) (P = 0.016). The radiographic groups compared favorably with the intraoperative gap length groups (P < 0.001). The need for postoperative ventilation (70.83% in Group A vs. 36.84% in Group C, P = 0.032) and mortality (62.5%, 26.9% and 15.8% in Group A, B, and C, respectively, P = 0.003) co-related significantly with the gap length.
Conclusion: Birth weight had a direct reciprocal relationship with the gap length. Radiographic assessment correlated with intraoperative gap length. Higher gap length was associated with increased need for postoperative ventilation and poor outcome.
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http://dx.doi.org/10.4103/0971-9261.182587 | DOI Listing |
Acta Biomater
January 2025
Central laboratory of Liaocheng People's Hospital, Liaocheng, Shandong, 252000, China. Electronic address:
Peripheral nerve injury (PNI) as a common clinical issue that presents significant challenges for repair. Factors such as donor site morbidity from autologous transplantation, slow recovery of long-distance nerve damage, and deficiencies in local cytokines and extracellular matrix contribute to the complexity of effective PNI treatment. It is extremely urgent to develop functional nerve guidance conduits (NGCs) as substitutes for nerve autografts.
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January 2025
Associate Professor, Division of Oral Diagnostic Sciences, School of Dentistry, Oregon Health & Science University, Portland, OR, USA.
Objectives: To compare a novel photon-counting sensor, two CBCT protocols and two CMOS sensors on the detection of gaps between a gutta-percha cone and root canal walls.
Methods: Twenty-five mandibular incisors were prepared to 45/.04 (size/taper) at working length.
PLoS One
January 2025
Cooperative Innovation Center of Unconventional Oil and Gas, Yangtze University (Ministry of Education & Hubei Province), Wuhan, Hubei, China.
This paper develops a finite element analysis model to investigate the seepage characteristics of cement sheaths, considering the flow properties of their porous medium. The model's applicability under various conditions was evaluated through grid sensitivity tests and model validation, indicating that it effectively captures the seepage behavior of cement sheaths with a reasonable degree of reliability. Key parameters, including cement sheath length, permeability, gap structure, pressure differential, and fluid properties, were analyzed using finite element methods to determine their impact on seepage flow.
View Article and Find Full Text PDFSci Rep
January 2025
Division of Public Health Science, Department of Health Sciences, Mid Sweden University, Sundsvall, Sweden.
Intimate Partner Violence (IPV) during pregnancy poses a serious threat to maternal health, particularly in low- and lower-middle-income countries (LMICs). Despite these known risks, the role of spousal educational differences in IPV during pregnancy remains poorly understood. This study aimed to examine this influence, analyzing data from multiple countries across five continents.
View Article and Find Full Text PDFJ Hazard Mater
January 2025
Chinese-German Joint Laboratory for Natural Product Research, Shaanxi International Cooperation Demonstration Base, Shaanxi University of Technology, Hanzhong, Shaanxi 723000, China; Centre of Molecular & Environmental Biology, Department of Biology, University of Minho, Braga 4710-057, Portugal; Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada. Electronic address:
The increasing environmental prevalence of micro/nano plastics (MNPs) has raised significant concerns regarding their potential impact on human health, particularly in terms of immunotoxicity. However, the direct effects of MNPs on immune molecules, especially how they may influence protein liquid-liquid phase separation (LLPS)-a critical process implicated in various aspects of immune function-remain largely unexplored. This study addresses this gap by investigating the effects of polystyrene nanoparticles (PS NPs) with different surface modifications and sizes on LLPS in immunoglobulin Y (IgY) antibodies, critical components of the avian immune system.
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