Severe Paracoccidioidomycosis in a 14-Year-Old Boy.

Mycopathologia

Department of Clinical Pathology, School of Medical Sciences, State University of Campinas (UNICAMP), Rua Tessalia Vieira de Camargo, 126, Campinas, São Paulo, 13083-878, Brazil.

Published: December 2016

Paracoccidioidomycosis (PCM) is the most important systemic mycoses in Latin America. We describe a severe case of paracoccidioidomycosis in a 14-year-old boy, with a rapid disease progression. The fungal strain was isolated and inoculated into a T and/or B cell immunocompromised mice, which revealed a highly virulent strain. The case report presented herein emphasizes the importance of considering PCM in the differential diagnosis of patients with other infectious diseases in endemic areas and highlights a novel isolate.

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http://dx.doi.org/10.1007/s11046-016-0035-2DOI Listing

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Severe Paracoccidioidomycosis in a 14-Year-Old Boy.

Mycopathologia

December 2016

Department of Clinical Pathology, School of Medical Sciences, State University of Campinas (UNICAMP), Rua Tessalia Vieira de Camargo, 126, Campinas, São Paulo, 13083-878, Brazil.

Paracoccidioidomycosis (PCM) is the most important systemic mycoses in Latin America. We describe a severe case of paracoccidioidomycosis in a 14-year-old boy, with a rapid disease progression. The fungal strain was isolated and inoculated into a T and/or B cell immunocompromised mice, which revealed a highly virulent strain.

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We present two cases of juvenile form of paracoccidioidomycosis (PCM), a systemic mycosis frequently found in rural areas, whose prognosis is poor in children and young adults. They are a 14-year-old boy and a 25-year-old woman, both residents in an urban area in São Paulo - Brazil, without any history of travelling to an endemic area. They have been admitted to the hospital due to fever, weight loss and lymphadenopathy.

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