AI Article Synopsis
- Myopic choroidal neovascularization (mCNV) is a serious eye condition that mainly affects younger patients with pathologic myopia and can significantly impact their quality of life.
- Traditional treatments, like photodynamic therapy, have had limited success, leading to a search for more effective options.
- Anti-vascular endothelial growth factor (anti-VEGF) therapy, previously used for age-related macular degeneration, has proven to be effective for mCNV and is now the preferred treatment method.
Article Abstract
Myopic choroidal neovascularization (mCNV) is the second most common form of CNV after age-related macular degeneration (AMD). It is a sight-threatening complication of pathologic myopia (PM) and often affects patients in their working years causing significant impact on quality of life. Previous therapies such as photodynamic therapy with verteporfin have shown limited success. Due to the similarities in pathogenesis of mCNV and AMD CNV, anti-vascular endothelial growth factor therapy (anti-VEGF), which has so far been the mainstay of treatment for AMD CNV, has been shown to be effective in the treatment of mCNV and has become the first-line treatment of choice. This article aims to examine briefly the epidemiology and pathophysiology of mCNV, as well as review the evidence for efficacy, safety, and clinical use of anti-VEGF treatment for mCNV.
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| http://dx.doi.org/10.1007/s40265-016-0605-0 | DOI Listing |
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