The 1983 Fatal Accident Reporting System (FARS) data and the Nationwide Personal Transportation Study (NPTS) exposure data were used to describe the major problems in night driving that involved older drivers, aged 65 or more, in fatal crashes and to assess their risk. One of the major findings was that the rate of involvement in fatal crashes in darkness of older drivers was much less than for drivers under the age of 25, but greater overall than for drivers aged 25-64. The rate for older females was much less than for older males. Although the overall fatal crash involvement of older drivers is not a serious cause for alarm at this time, the performance of older males does indicate a substantial increase in risk of fatal crash involvement in darkness. These trends can be expected to become more noticeable over the years as a greater proportion of the population in the United States exceeds the age of 65. The older driver crash involvement at night seems to be particularly troublesome for males in multivehicle crashes where they are struck in the side or rear by another vehicle, and single-vehicle crashes where they run off the road on a straight section. Some suggested improvements of the overall night driving environment are discussed.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/0001-4575(89)90018-3 | DOI Listing |
Immun Ageing
December 2024
Department of Biomedical Sciences, Institute of Health, Jimma University, Jimma, 378, Oromia, Ethiopia.
Immunosenescence, the slow degradation of immune function over time that is a hallmark and driver of aging, makes older people much more likely to be killed by common infections (such as flu) than young adults, but it also contributes greatly to rates of chronic inflammation in later life. Such micro nutrients are crucial for modulating effective immune responses and their deficiencies have been associated with dysfunctional immunity in the elderly. In this review, we specifically focused on the contribution of major micro nutrients (Vitamins A, D and E, Vitamin C; Zinc and Selenium) as immunomodulators in ageing population especially related to inflame-ageing process including autoimmunity.
View Article and Find Full Text PDFAcad Emerg Med
December 2024
Department of Emergency Medicine, Hennepin Healthcare, Minneapolis, Minnesota, USA.
Background: Sepsis remains the leading cause of in-hospital death and one of the costliest inpatient conditions in the United States, while treatment delays worsen outcomes. We sought to determine factors and outcomes associated with a missed emergency physician (EP) diagnosis of sepsis.
Methods: We conducted a secondary analysis of a prospective single-center observational cohort of undifferentiated, critically ill medical patients (September 2020-May 2022).
Aging Clin Exp Res
December 2024
MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.
Mild cognitive impairment, dementia and osteoporosis are common diseases of ageing and, with the increasingly ageing global population, are increasing in prevalence. These conditions are closely associated, with shared risk factors, common underlying biological mechanisms and potential direct causal pathways. In this review, the epidemiological and mechanistic links between mild cognitive impairment, dementia and skeletal health are explored.
View Article and Find Full Text PDFJ Endocr Soc
November 2024
VA Northwest Mental Illness Research, Education and Clinical Center, VA Puget Sound Health Care System, Seattle, WA 98108, USA.
Context: Many studies have moved toward saliva and peripheral blood sampling for studying cortisol, even in relation to disorders of the brain. However, the degree to which peripheral cortisol reflects central cortisol levels has yet to be comprehensively described. Data describing the effect that biological characteristics such as age and sex have on cortisol levels across compartments is also limited.
View Article and Find Full Text PDFBiochim Biophys Acta Gen Subj
December 2024
Algal and Microbial Biotechnology Division, Faculty of Biosciences and Aquaculture, Nord University, Universitetsalléen 11, 8026 Bodø, Norway.
Factors influencing variance of DNA methylation in vegetatively reproducing plants, both terrestrial plants and aquatic seagrasses, is just beginning to be understood. Improving our knowledge of these mechanisms will increase understanding of transgenerational epigenetics in plant clones, of the relationship between DNA methylation and seagrass development, and of the drivers of epigenetic variation, which may underly acclimation in clonally reproducing plants. Here, we sampled leaves, rhizomes and roots of three physically and spatially separated ramet sections from a clonally propagated field of the seagrass Zostera marina.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!