Epilepsy surgery in Sturge-Weber syndrome.

Aust Paediatr J

Department of Paediatric Nuerology, Prince of Wales Children's Hospital, Randwick, Australia.

Published: April 1989

AI Article Synopsis

  • A 13-year-old patient with Sturge-Weber syndrome experienced severe seizures characterized by significant visual symptoms, stemming from the condition since she was 4 years old.
  • Medical imaging revealed progressive bilateral occipital lesions, particularly severe changes in the right hemisphere, indicating targeted epileptogenic activity.
  • After extensive surgical removal of the right occipital lobe, the patient reported only seven brief seizures in the year following the operation, suggesting that surgery can effectively treat intractable seizures in certain cases involving complex brain pathology.

Article Abstract

A patient with Sturge-Weber syndrome developed seizures at the age of 4 years. At 13 years of age, she had intractable complex partial seizures with marked visual symptomatology. Interictal encephalograms showed bilateral slow activity, more marked over the right hemisphere with epileptogenic activity maximal in the right temporal region. Serial computerized axial tomography scans demonstrated evolution of bilateral occipital lesions with calcification and adjacent low density areas that were more marked on the right. Magnetic resonance imaging, angiography and neuropsychological evaluations were performed. An extensive resection of the right occipital lobe was achieved. One year after surgery, the patient has had seven brief seizures. Delineation of an epileptogenic focus and surgical removal of the lesion in patients with intractable seizures can now be considered in selected patients with bilateral central nervous system pathology.

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Source
http://dx.doi.org/10.1111/j.1440-1754.1989.tb01428.xDOI Listing

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