Objective: To study the chemical constituents of flower buds of Lonicera similis.

Methods: The compounds were isolated and repeatedly purified by macroperous resin, silica gel column, gel column, preparation of TLC, and RP C18, chromatography. Their structures were elucidated by physicochemical properties, MS and NMR.

Results: Seven compounds were isolated and identified as 4-hydroxy-γ,3,5-trimethoxybenzenepropanol (1), ursolic acid(2), E-ferulic acid(3), caffeic acid ethyl ester(4), dihydrosyringenin (5), rutin(6) and 6-Daucosterin (7).

Conclusion: Compounds 1 and 5 are isolated from this genus for the first time, and compounds 2 - 4 are isolated from this plant for the first time.

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