Objective: To study the ethyl acetate-soluble chemical constituents of Callicarpa kwangtungensis.
Methods: The chemical constituents were isolated by column chromatography on silica gel, Sephadex LH-20 and MPLC. Their chemical structures were elucidated on the basis of special analysis.
Results: Eleven compounds were isolated from the ethyl acetate-soluble part of Callicarpa kwangtungensis, whose structures were elucidated as 4-methoxybenzoic acid (1), 3,4-dihydroxybenzoic acid (2), 4-hydroxy cinnamic acid(3), phenyl-β-D-glucopyranoside (4), 3,4,5-trimethoxyphenyl-β-D-glucopyranoside (5), 2α,3β,22β,23-tetrahydroxyursolic-12-en-28-oic acid (6), 2α,3β,6β,19α-tetrahydroxy-urs-12-en-28-O-β-D-glucopyranoside (7), 2β,3β,6β,16α-tetrahydroxy-olean-12-en-28-O-β-D-glucopyranoside (8), (3S, 6E, 10R)-10-β-D-glucopyranosyloxy-3,11-dihydroxy-3,7,11-trimethyldodeca-1,6-diene (9), icariside C5(10), and (2E, 6E)-10-β-D-glucopyranosyl-1, 11-dihydroxy-3, 7, 11-trimethyldodeca-2,6-diene (11).
Conclusion: Compounds 4 - 11are isolated from Callicarpa genus for the first time, compounds 1 - 3 are isolated from this plant for the first time.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Lapsi (Roxb.) B.L.Burtt & A.W.Hill): A review on traditional uses, chemical constituents and biological activities.
Heliyon
January 2025
Pharmacy Program, Gandaki University, Pokhara, 33700, Nepal.
Lapsi ( (Roxb.) B.L.
View Article and Find Full Text PDFAim Of The Study: This study investigated the mechanism by which the Postoperative Tongqi Formula (PTQF) treats postoperative ileus (POI) through regulation of the p38 MAPK signaling pathway, Zona occludens 1 (ZO-1) protein, and metabolism.
Methods: The primary components of PTQF were characterized using UHPLC-Q-TOF-MS/MS. The identified compounds subsequently employed network pharmacology to predict the signaling pathways associated with the inflammatory phase of POI.
Exploring the Versatility of Azine Derivatives: A Comprehensive Review on Synthesis and Biological Applications.
Mini Rev Med Chem
January 2025
Department of Chemistry, Abdul Wali Khan University, Mardan, 23200, Pakistan.
Organic compounds containing azines, di-imines, or bis-Schiff-bases have two azomethine (-CH=N-) functional groups associated with a bridging component. These constituents have attracted attention from a diversity of disciplines, comprising coordination, medicinal, agriculture chemistry, and organic synthesis, because of their comprehensive chemical reactivity and nature. This study determines common synthetic approaches and various biological and pharmacological activities of several substituted bis-Schiff byproducts.
View Article and Find Full Text PDFAnalyzing How Zhizi Baipi Decoction Regulates VEGF to Suppress RA Angiogenesis Using Network Pharmacology and Experimental Validation.
Phytochem Anal
January 2025
College of Pharmacy, Anhui University of Chinese Medicine, Hefei, China.
Introduction: Rheumatoid arthritis (RA) is a chronic autoimmune disease that primarily manifests with symptoms such as heat and toxin. However, the key components and molecular mechanisms of Zhizi Baipi decoction (ZBD) in the treatment of RA are still unclear.
Objectives: The study aimed to explore the mechanism of action of ZBD for treating RA through ingredient analysis, network pharmacology, and experimental validation.
Chemical Fingerprinting and Multivariate Analysis of Different Grades of Farfarae Flos Using HPLC and UPLC-ESI-Q/TOF-MS/MS.
Phytochem Anal
January 2025
School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.
Introduction: Farfarae Flos is widely used as a traditional herbal medicine. Currently, its size has been the primary grading criterion used in market circulation. Whether this empirical criterion can accurately reflect the quality of the medicinal material has not been systematically studied.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!