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http://dx.doi.org/10.1056/NEJMc1605896 | DOI Listing |
N Engl J Med
June 2016
Hospital of the University of Pennsylvania, Philadelphia, PA.
N Engl J Med
March 2016
Dr. Rosenbaum is a national correspondent for the Journal.
Philos Trans R Soc Lond B Biol Sci
May 2014
Institute of Ecological Sciences, Faculty of Earth and Life Sciences, Vrije Universiteit, , De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands.
Trade-offs between individual fitness and the collective performance of crop and below-ground symbiont communities are common in agriculture. Plant competitiveness for light and soil resources is key to individual fitness, but higher investments in stems and roots by a plant community to compete for those resources ultimately reduce crop yields. Similarly, rhizobia and mycorrhizal fungi may increase their individual fitness by diverting resources to their own reproduction, even if they could have benefited collectively by providing their shared crop host with more nitrogen and phosphorus, respectively.
View Article and Find Full Text PDFNature
May 2006
NERC Center for Population Biology, Imperial College London, Silwood Park Campus, Ascot, Berkshire SL5 7PY, UK.
Understanding the conditions that promote the maintenance of cooperation is a classic problem in evolutionary biology. The essence of this dilemma is captured by the 'tragedy of the commons': how can a group of individuals that exploit resources in a cooperative manner resist invasion by 'cheaters' who selfishly use common resources to maximize their individual reproduction at the expense of the group? Here, we investigate this conflict through experimental competitions between isogenic cheater and cooperator strains of yeast with alternative pathways of glucose metabolism, and by using mathematical models of microbial biochemistry. We show that both coexistence and competitive exclusion are possible outcomes of this conflict, depending on the spatial and temporal structure of the environment.
View Article and Find Full Text PDFCNS Spectr
August 2002
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, CA, USA.
This article reports on the planning, development, and implementation of a large national Internet-based panel study of how Americans are coping with the terrorist attacks of September 11, 2001. The study was designed to determine predictors and correlates of risk and resilience, both cross-sectionally and longitudinally. In order to acquire timely and meaningful data, we developed/adapted an extensive set of measures, obtained human subjects approval, and posted a research Web site just 17 days after the attacks.
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