On Study of Immune Response to Tumor Cells in Prey-Predator System.

Int Sch Res Notices

Department of Mathematics, Jamia Millia Islamia, Jamia Nagar, New Delhi 110025, India.

Published: June 2016

This paper aims to develop the mathematical model that explores the immune response to a tumor system as a prey-predator system. A deterministic model defining the dynamics of tumor growth progression and regression has been analyzed. Our analysis indicates the tumor recurring and dormancy on the cellular level in combination with resting and hunting cells. The model considered in the present study is a generalization of El-Gohary (2008) by introducing the Michaelis-Menten function. This function describes the stimulation process of the resting cells by the tumor cells in the presence of tumor specific antigens. Local and global stability analysis have been performed along with the numerical simulation to support our findings.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897590PMC
http://dx.doi.org/10.1155/2014/346597DOI Listing

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