Objective: To identify symptoms, common diagnostic findings, pattern of treatments and referrals offered, and their efficacy in a group of patients with idiopathic functional dysphagia in an otolaryngology setting with multiple providers.
Study Design: Case series with chart review.
Setting: Tertiary academic center.
Subjects And Methods: Following Mayo Clinic Institutional Review Board approval, a retrospective chart review was conducted of patients with dysphagia who had a videofluoroscopic swallow study between January 1, 2013, and April 30, 2015. Each patient's dysphagia symptomology, videofluoroscopic swallow study, flexible laryngoscopy, and medical chart were reviewed to identify the treatment paradigms that were utilized.
Results: Sixty-seven adult patients met the inclusion criteria. Abnormal laryngeal muscle tension was present in 97% of patients. Eighty-two percent of patients also demonstrated signs of laryngeal hyperresponsiveness. Nonspecific laryngeal inflammation was evident in 52% of patients. Twenty-seven patients were referred to speech-language pathology for evaluation. Thirteen patients completed a course of voice therapy directed toward unloading muscle tension. All 13 patients self-reported resolution of dysphagia symptoms.
Conclusion: The study results suggest that laryngeal muscle tension may be a factor in the underlying etiology in patients with idiopathic functional dysphagia. We propose the diagnostic term muscle tension dysphagia to describe a subset of patients with functional dysphagia. Further prospective studies are needed to better evaluate potential gastroesophageal confounders in this group of patients and to identify an effective paradigm for treatment. In our limited series, speech-language pathology intervention directed toward unloading muscle tension appears effective.
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http://dx.doi.org/10.1177/0194599816657013 | DOI Listing |
Nutrients
January 2025
State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products, Ningbo University, Ningbo 315211, China.
Background: , which are filamentous cyanobacteria, have gained significant popularity in the food industry, medicine, and aquaculture.
Methods: In this study, our objective was to explore the influence of on the gut microbiota and exercise capacity of mice undergoing high-intensity exercise. Twenty-four male BALB/c mice were divided into four groups, with six mice in each group.
Bioengineering (Basel)
December 2024
Chair of Modelling in Engineering Sciences and Medicine, Faculty of Mechanical Engineering, University of Ljubljana, Aškerčeva c. 6, 1000 Ljubljana, Slovenia.
The Lateral Collateral Ligament (LCL), one of the four major ligaments in the knee joint, resides on the outer aspect of the knee. It forms a vital connection between the femur and the fibula. The LCL's primary role is to provide stability against Varus forces, safeguarding the knee from undue rotation and tibial displacement.
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December 2024
Rehabilitation Medicine, Spine Center, Bologna, ITA.
In the past two decades, interest in the fascial system has exponentially increased, particularly manual treatment and stretching exercises. The fascia's fundamental role remains the transmission of tensions, although this function can be impaired due to excessive or reduced stiffness. This second part of the work outlines the basic principles concerning the importance of appropriate and balanced fascial stiffness for correct postural and functional maintenance of the human body.
View Article and Find Full Text PDFJ Physiol Sci
January 2025
Department of Cell Physiology, The Jikei University School of Medicine, 3-25-8 Nishi-Shimbashi, Minato-Ku, 105-8461, Tokyo, Japan.
Of the ions involved in myocardial function, Ca is the most important. Ca is crucial to the process that allows myocardium to repeatedly contract and relax in a well-organized fashion; it is the process called excitation-contraction coupling. In order, therefore, for accurate comprehension of the physiology of the heart, it is fundamentally important to understand the detailed mechanism by which the intracellular Ca concentration is regulated to elicit excitation-contraction coupling.
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January 2025
Department of General Surgery, Ankara Medipol University Faculty of Medicine, Ankara, Türkiye.
Background/aims: Levator ani syndrome (LAS) is a pathology that is both difficult to diagnose and treat. The effectiveness of current treatments, which are mostly administered with special devices in advanced healthcare centers, is controversial. The aim of the study is to investigate the effects of glyceryl trinitrate, which is easily accessible and can be applied by the patient, in the treatment of LAS.
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