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Urinary Catheter Utility in Laparoscopic Appendectomy: Risk Benefit Analysis of Post-Operative Urinary Tract Complications.
Surg Infect (Larchmt)
December 2024
Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.
Catheter-associated urinary tract infections (CAUTIs) account for 1 million nosocomial infections annually and 75% of all hospital-acquired UTIs. A risk factor for CAUTI is prolonged urinary catheterization (UC); therefore, transitory UC during laparoscopic appendectomy (LA), a common practice justified to avoid iatrogenic bladder injury, is believed to be safe. However, data on the incidence of post-operative UC-related complications, including CAUTI, following LA or their avoidance are limited.
View Article and Find Full Text PDFA decade-long overview of adverse events in a tertiary surgical service in South Africa.
S Afr Med J
October 2024
Department of Surgery, Faculty of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
Article Synopsis
- Adverse events in healthcare are prevalent and can negatively affect both patients and the healthcare system, particularly highlighted by a lack of South African data.
- The study analyzed ten years of electronic medical records from December 2012 to January 2023, documenting 14,537 adverse events from over 52,000 admissions, which represents an overall rate of 22%.
- The majority of adverse events were related to clinical care, with significant occurrences linked to indwelling devices and iatrogenic injuries, emphasizing the need for a comprehensive approach to reduce these incidents.
Comparative genome analysis reveals putative and novel antimicrobial resistance genes common to the nosocomial infection pathogens.
Microb Pathog
December 2024
Department of Pharmaceutical Biology, Faculty of Pharmaceutical Sciences, UCSI University, Cheras, 56000, Kuala Lumpur, Malaysia. Electronic address:
The 21st century has witnessed several clinical outcomes regarding AMR. One health concept has been foreseen as a standard global public health initiative in ensuring human, animal and environmental health. The present study explores critical Gram-negative ESKAPE pathogens encompassing Acinetobacter baumannii (ACB), Klebsiella pneumoniae (KPX) and Pseudomonas aeruginosa (PAE).
View Article and Find Full Text PDFLow-Dose Planned Glucarpidase Allows Safe Outpatient High-Dose Methotrexate Treatment for CNS Lymphoma.
JCO Oncol Pract
October 2024
Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY.
Article Synopsis
- * A study tested the feasibility of administering HD-MTX in an outpatient setting with the aid of low-dose glucarpidase to help clear the drug more quickly.
- * Results showed that all treatments were effective and safe, with no hospitalizations needed, suggesting that outpatient HD-MTX with glucarpidase could change how CNS lymphoma is treated.
Preventing iatrogenic HCV infection: A quantitative risk assessment based on observational data in an Egyptian hospital.
PLOS Glob Public Health
February 2024
MESuRS Laboratory, Conservatoire national des arts et métiers, Paris, France.
When compliance with infection control recommendations is non-optimal, hospitals may play an important role in hepatitis C (HCV) transmission. However, few studies have analyzed the nosocomial HCV acquisition risk based on detailed empirical data. Here, we used data from a prospective cohort study conducted on 500 patients in the Ain Shams hospital (Cairo, Egypt) in 2017 with the objective of identifying (i) high-risk patient profiles and (ii) transmission hotspots within the hospital.
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