AI Article Synopsis
- The study investigated the impact of a single dose of the hormone triptoreline on pregnancy success during natural-cycle frozen embryo transfers, involving 98 women divided into an intervention group and a control group.
- Results showed higher rates of positive pregnancy tests, clinical pregnancies, and live births in the triptoreline group, but these findings were not statistically significant.
- Additionally, the triptoreline group had significantly lower levels of beta hCG in singleton pregnancies, while there was no notable difference in newborn birth weights between the groups.
Article Abstract
This prospective randomised crossover study evaluated the effect of mid-luteal single-dose gonadotropin-releasing hormone agonist (triptoreline) on pregnancy outcomes in natural-cycle frozen embryo transfers (FETs). Ninety-eight women were randomised to receive either standard luteal support with vaginal micronised progesterone or an additional single dose of 0.1 mg triptoreline at the time of implantation. The intervention group was composed of 65 FET cycles and the control group of 62 cycles. In the intervention group, there were more positive pregnancy tests, clinical pregnancies and live births, but the differences did not reach statistical significance. The mean beta human chorionic gonadotropin (β-hCG) concentration of singleton pregnancies was significantly lower in the intervention group compared to the control group (p = 0.048). No difference was detected in the median birth weight of the newborns.
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| http://dx.doi.org/10.1080/09513590.2016.1196176 | DOI Listing |
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