Gut microbiota and hematopoietic stem cell transplantation: where do we stand?

Bone Marrow Transplant

Pediatric Oncology and Haematology Unit 'Lalla Seràgnoli', Department of Pediatrics, University of Bologna, Sant'Orsola Malpighi Hospital, Bologna, Italy.

Published: January 2017

Advances in biological techniques have potentiated great progresses in understanding the interaction between human beings and the ∼10 to 100 trillion microbes living in their gastrointestinal tract: gut microbiota (GM). In this review, we describe recent emerging data on the role of GM in hematopoietic stem cell transplantation, with a focus on immunomodulatory properties in the immune system recovery and the impact in the development of the main complications, as GvHD and infections.

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Source
http://dx.doi.org/10.1038/bmt.2016.173DOI Listing

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