Study Design: The study aimed to build a new cervical artificial disc C3-C7 segment prosthesis, and perform a biomechanical comparison between the new prosthesis and the Prestige LP prosthesis using a three-dimensional non-linear finite element (FE) model.
Purpose: The study compared the biomechanical differences between the new cervical artificial disc prosthesis based on the physiological curvature of the end plate and the Prestige LP prosthesis after artificial disc replacement.
Background Context: There has been no prior research on artificial disc prostheses based on the physiological curvature of the end plate; studies of biomechanical changes after cervical disc arthroplasty (CDR) are few.
Methods: An FE model of the C3-C7 segments was developed and validated. A new cervical artificial disc prosthesis based on the physiological curvature of the end plate and the Prestige LP prosthesis were integrated at the C5-C6 segment into the validated FE model. All models were subjected to a follower load of 73.6 N and a 1 Nm in flexion-extension, lateral bending, and axial torsion. The segmental range of motion (ROM) and stress on the prostheses were analyzed.
Results: The ROM in most segments after CDR with new cervical artificial disc prosthesis was more similar to that of the normal cervical spine than the Prestige LP prosthesis. However, there was no significant difference between the two prostheses. The stress on the new artificial disc was significantly less than that in the Prestige LP prosthesis.
Conclusions: There was no significant difference in ROM in all segments after CDR for the two prostheses. The stress on the new cervical artificial disc prosthesis based on the physiological curvature of the end plate was significantly less than that in the Prestige LP prosthesis. The new artificial disc prosthesis is feasible and effective, and can reduce the implant-bone interface stress on the end plate, which may be one of the causes of prosthesis subsidence.
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http://dx.doi.org/10.1016/j.spinee.2016.06.019 | DOI Listing |
Expert Rev Med Devices
January 2025
UC Davis Health.
Introduction: The Mobi-C Cervical Disc Replacement is a motion preserving alternative to anterior cervical discectomy and fusion in properly indicated patients. In 2013, Mobi-C became the first cervical disc in the United States approved to treat more than one level of the cervical spine. The FDA determined Mobi-C to be statistically superior to fusion at 2 levels, based on the primary endpoint of a prospective, concurrently controlled and randomized multicenter clinical trial.
View Article and Find Full Text PDFClin Ophthalmol
December 2024
Department of Ophthalmology, Cliniques Universitaires Saint Luc, UCL, Brussels, Belgium.
Purpose: This study aims to evaluate the inter-observer variability in assessing the optic disc in fundus photographs and its implications for establishing ground truth in AI research.
Methods: Seventy subjects were screened during a screening campaign. Fundus photographs were classified into normal (NL) or abnormal (GS: glaucoma and glaucoma suspects) by two masked glaucoma specialists.
Med Intensiva (Engl Ed)
December 2024
IRCCS Policlinico San Martino, Genova, Italy; Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.
Objective: The relationship between different power equations and the severity of acute respiratory distress syndrome (ARDS) remains unclear. This study aimed to evaluate various power equations: total mechanical power, total elastic power (comprising elastic static and elastic dynamic power), and resistive power, in a cohort of mechanically ventilated patients with and without ARDS. Bayesian analysis was employed to refine estimates and quantify uncertainty by incorporating a priori distributions.
View Article and Find Full Text PDFCureus
November 2024
General Dentistry and Comprehensive Care, NYU College of Dentistry, New York University, New York, USA.
Objectives To assess the influence of cigarette smoke (CS) on the color and surface roughness of 3D printed, milled, and traditionally fabricated provisional crown and bridge (PC&B) materials. Materials and methods 112 disc-shaped samples were made employing four techniques and materials (28 per group) to fabricate PC&B prostheses. Specimens were fabricated using standard protocols, such as 3D printing, milling, conventional bis-acrylic resin, and traditional autopolymerizing polymethyl methacrylate (PMMA) resin.
View Article and Find Full Text PDFSpine J
December 2024
Department of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University.. Electronic address:
Background Context: Hybrid surgery (HS), which involves both anterior cervical discectomy and fusion (ACDF) and cervical disc replacement (ACDR), is increasingly used to treat multilevel cervical disc degenerative disease, yielding satisfactory clinical outcomes. Early fusion is critical after anterior cervical fusion surgeries, but there are no studies comparing the rate of early fusion of HS with that of ACDF.
Purpose: The purpose of this study was to compare the rate of early fusion (3-6 months postoperatively) of two-level HS with that of two-level ACDF surgery.
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