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Background: Computed tomography scans are widely used in everyday medical practice due to speed, image reliability, and detectability of a wide range of pathologies. Each scan exposes the patient to a radiation dose, and performing a fast estimation of the effective dose (E) is an important step for radiological safety. The aim of this work is to estimate E from patient and CT acquisition parameters in the absence of a dose-tracking software exploiting machine learning.

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Non-diffuse materials (e.g., metallic inks, varnishes, and paints) are widely used in real-world applications.

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Rapid Acquisition of High-Pixel Fluorescence Lifetime Images of Living Cells via Image Reconstruction Based on Edge-Preserving Interpolation.

Biosensors (Basel)

January 2025

State Key Laboratory of Radio Frequency Heterogeneous Integration (Shenzhen University), Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, China.

Fluorescence lifetime imaging (FLIM) has established itself as a pivotal tool for investigating biological processes within living cells. However, the extensive imaging duration necessary to accumulate sufficient photons for accurate fluorescence lifetime calculations poses a significant obstacle to achieving high-resolution monitoring of cellular dynamics. In this study, we introduce an image reconstruction method based on the edge-preserving interpolation method (EPIM), which transforms rapidly acquired low-resolution FLIM data into high-pixel images, thereby eliminating the need for extended acquisition times.

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Optimizing complex systems usually involves costly and time-consuming experiments, where selecting the experiments to perform is fundamental. Bayesian optimization (BO) has proved to be a suitable optimization method in these situations thanks to its sample efficiency and principled way of learning from previous data, but it typically requires that experiments are sequentially performed. Fully distributed BO addresses the need for efficient parallel and asynchronous active search, especially where traditional centralized BO faces limitations concerning privacy in federated learning and resource utilization in high-performance computing settings.

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Despite the presentation of similar psychological symptoms, psychological dysfunction secondary to brain injury exhibits markedly lower treatment efficacy compared to injury-independent psychological dysfunction. This gap remains evident, despite extensive research efforts. This review integrates clinical and preclinical evidence to provide a comprehensive overview of the neurobiological mechanisms underlying neuropsychological disorders, focusing on the role of key brain regions in emotional regulation across various forms of brain injuries.

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