Background: Failure to rescue (FTR) is increasingly recognized as an important quality indicator in surgery. The Society of Thoracic Surgeons National Database was used to develop FTR metrics and a predictive FTR model for coronary artery bypass grafting (CABG).

Methods: The study included 604,154 patients undergoing isolated CABG at 1,105 centers from January 2010 to January 2014. FTR was defined as death after four complications: stroke, renal failure, reoperation, and prolonged ventilation. FTR was determined for each complication and a composite of the four complications. A statistical model to predict FTR was developed.

Results: FTR rates were 22.3% for renal failure, 16.4% for stroke, 12.4% for reoperation, 12.1% for prolonged ventilation, and 10.5% for the composite. Mortality increased with multiple complications and with specific combinations of complications. The multivariate risk model for prediction of FTR demonstrated a C index of 0.792 and was well calibrated, with a 1.0% average difference between observed/expected (O/E) FTR rates. With centers grouped into mortality terciles, complication rates increased modestly (11.4% to 15.7%), but FTR rates more than doubled (6.8% to 13.9%) from the lowest to highest terciles. Centers in the lowest complication rate tercile had an FTR O/E of 1.14, whereas centers in the highest complication rate tercile had an FTR O/E of 0.91.

Conclusions: CABG mortality rates vary directly with FTR, but complication rates have little relation to death. FTR rates derived from The Society of Thoracic Surgeons data can serve as national benchmarks. Predicted FTR rates may facilitate patient counseling, and FTR O/E ratios have promise as valuable quality metrics.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.athoracsur.2016.04.051DOI Listing

Publication Analysis

Top Keywords

ftr rates
20
ftr
16
society thoracic
12
thoracic surgeons
12
ftr o/e
12
rates
9
failure rescue
8
coronary artery
8
artery bypass
8
bypass grafting
8

Similar Publications

Impact of anastomotic leak vs pneumonia on failure to rescue after transthoracic esophagectomy for cancer.

J Gastrointest Surg

January 2025

Paracelsus Medical University, Nuremberg, Germany; Paracelsus Medical University, Salzburg, Austria; Department of Surgery, Helios Clinic Erfurt, Academic Hospital of the University of Jena, Erfurt, Germany.

Background: Data about failure to rescue (FTR) after esophagectomy for cancer and its association with patient and procedure-related risk factors are limited. This study aimed to analyze such aspects, particularly focusing on the effect of pneumonia and anastomotic leak on FTR.

Methods: Patients who underwent an Ivor Lewis esophagectomy for cancer between 2008 and 2022 in 2 tertiary European centers were prospectively identified.

View Article and Find Full Text PDF

Background: Pancreatic ductal adenocarcinoma (PDAC) typically occurs in an older patient population. Yet, early-onset pancreatic cancer (EOPC) has one of the fastest growing incidence rates. This study investigated the influence of age and tumor location on postoperative morbidity and mortality in a large, real-world dataset.

View Article and Find Full Text PDF

Climate change introduces greater thermal variability, profoundly affecting ectothermic species whose body temperatures rely heavily on the environment. Understanding the physiological and metabolic responses to such variability is crucial for predicting how these species will cope with changing climates. This study investigates how chronic thermal stress impacts mitochondrial metabolism and physiological parameters in Drosophila melanogaster, hypothesizing that a fluctuating thermal regime (FTR) activates protective mechanisms enhancing stress tolerance and longevity.

View Article and Find Full Text PDF

Weekday effect of surgery on in-hospital outcome in pancreatic surgery: a population-based study.

Langenbecks Arch Surg

December 2024

Department of Visceral, Transplant and Thoracic Surgery, Frankfurt am Main University Medical Center, Theodor- Stern-Kai 7, 60596, Frankfurt am Main, Germany.

Importance: There is conflicting evidence regarding weekday dependent outcome in complex abdominal surgery, including pancreatic resections.

Objective: To clarify weekday-dependency of outcome after pancreatic resections in a comprehensive nationwide context.

Design: Retrospective cross-sectional study of anonymized nationwide hospital billing data (DRG data).

View Article and Find Full Text PDF

Background: Sepsis disproportionately affects marginalized communities. This study aims to evaluate racial and ethnic disparities in failure-to-rescue (FTR) after postoperative sepsis.

Methods: This cross-sectional study used data from the American College of Surgeons National Surgical Quality Improvement Program for patients who underwent inpatient noncardiac surgery between 2018 and 2021.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!