STAT Assays with a TWIST: Differentiating Sézary Syndrome from Erythrodermic Inflammatory Dermatitis.

J Invest Dermatol

Department of Dermatology, University of Arkansas for Medical Science, Little Rock, Arkansas, USA. Electronic address:

Published: July 2016

Sézary syndrome can be challenging to differentiate from erythrodermic inflammatory dermatitis. Biomarkers have been identified in Sézary syndrome, but have not been validated in multicenter studies in a cohort that allows comparisons. Boonk et al. now describe results that confirm the value of immunophenotype, and they report higher sensitivity and specificity for a set of genes used to distinguish Sézary syndrome from erythrodermic inflammatory dermatitis.

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http://dx.doi.org/10.1016/j.jid.2016.05.087DOI Listing

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