Background: Constraint Induced Aphasia Therapy (CIAT) has been shown to be effective in the treatment of aphasia, but clinicians have expressed concern regarding how far CIAT is practical to implement in clinical practice.
Objective: To determine whether CIAT delivered in a less-intense, lower dose, reduced constraint and volunteer-led format could produce positive outcomes in people with chronic aphasia.
Methods: Two groups were run, each with two people with chronic aphasia. Treatment involved a standard CIAT card-exchange game, supplemented by a home activity. Spoken language was required for responses but alternative modalities of communication were also permitted. Each group was led by a trained volunteer, lasted 90 minutes and was delivered twice a week for four weeks.
Results: Three of the four participants showed significant improvements in target word retrieval following treatment. No significant improvements were observed for untreated stimuli or language tasks. Two participants showed increases in the elaboration of their responses, and the same two showed an increase in the frequency with which they engaged in communication activities.
Conclusions: Clear gains in performance were observed for the majority of people with aphasia who participated in a less intense format, considerably lower dose and less constrained form of CIAT led by trained volunteers. This suggests that this 'clinically realistic' service delivery model for CIAT could be added to the clinical repertoire of speech pathologists.
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http://dx.doi.org/10.3233/NRE-161341 | DOI Listing |
Digit Health
January 2025
Ohad Cohen Endocrinology, Tel Hashomer, Israel.
Objective: The objective of this pilot study is to evaluate the feasibility of using an automatic weight management system to follow patients' response to weight reduction medications and to identify early deviations from weight trajectories.
Methods: The pilot study involved 11 participants using Semaglutide for weight management, monitored over a 12-month period. A cloud-based, Wi-Fi-enabled remote weight management system collected and analyzed daily weight data from smart scales.
Materials (Basel)
January 2025
School of Aeronautic Science and Engineering, Beihang University, Beijing 100191, China.
The structure of thermoset composite laminated plates is made by stacking layers of plies with different fiber orientations. Similarly, the stiffened panel structure is assembled from components with varying ply configurations, resulting in thermal residual stresses and processing-induced deformations (PIDs) during manufacturing. To mitigate the residual stresses caused by the geometric features of corner structures and the mismatch between the stiffener-skin ply orientations, which lead to PIDs in composite-stiffened panels, this study proposes a multi-objective stacking optimization strategy based on an improved adaptive genetic algorithm (IAGA).
View Article and Find Full Text PDFHealthcare (Basel)
January 2025
Allied Health Research Unit, St Vincent's Health Network Sydney, Darlinghurst, NSW 2010, Australia.
Constraint-induced movement therapy (CIMT) is an evidence-based intervention for arm recovery after acquired brain injury. Clinician knowledge, time and confidence in delivering CIMT are established barriers to the routine use of CIMT in practice. CIMT delivery via telehealth is one option to help overcome these barriers.
View Article and Find Full Text PDFCurr Biol
January 2025
Department of Earth Sciences, University of Oxford, Oxford OX1 3AN, UK.
Negative scaling relationships between both speciation and extinction rates, on the one hand, and the age or duration of organismal groups on the other, are pervasive and recovered in both molecular phylogenetic and fossil time series. The agreement between molecular and fossil data hints at a universal cause and potentially at incongruence between micro- and macroevolution. However, the existence of negative rate scaling in fossil time series has not undergone the same level of scrutiny as in molecular data.
View Article and Find Full Text PDFCurr Oncol
January 2025
Department of Radiation Oncology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing 100191, China.
(1) Background: Volumetric modulated arc therapy (VMAT) can deliver more accurate dose distribution and reduce radiotherapy-induced toxicities for postoperative cervical and endometrial cancer. This study aims to retrospectively analyze the relationship between dosimetric parameters of organs at risk (OARs) and acute toxicities and provide suggestions for the dose constraints. (2) Methods: A total of 164 postoperative cervical and endometrial cancer patients were retrospectively analyzed, and the endpoints were grade ≥ 2 acute urinary toxicity (AUT) and acute lower gastrointestinal toxicity (ALGIT).
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