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Colitis as the Sole Initial Presentation of Chronic Granulomatous Disease: Histopathologic Clues to Diagnosis. | LitMetric

Colitis as the Sole Initial Presentation of Chronic Granulomatous Disease: Histopathologic Clues to Diagnosis.

Pediatr Infect Dis J

From the *New York University School of Medicine, New York, New York; †Division of Pediatric Infectious Diseases, Department of Pediatrics, ‡Department of Pathology, and §Division of Pediatric Gastroenterology, Department of Pediatrics, New York University School of Medicine, New York, New York.

Published: November 2016

AI Article Synopsis

Article Abstract

Chronic granulomatous disease is a rare, inherited immunodeficiency disorder that reduces the superoxide generation ability of phagocytes, leading to recurrent infections and granulomatous inflammation. We report the case of a previously healthy 3-year-old boy who presented with classic features of Crohn disease. Suspicion from histopathologiclogic assessment allowed early diagnosis and treatment for chronic granulomatous disease before the onset of infections.

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Source
http://dx.doi.org/10.1097/INF.0000000000001284DOI Listing

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