Intramedullary osteosclerosis, a rare entity, is usually diagnosed after the exclusion of more sinister etiologies. It typically affects the lower extremity and is more common in females. While the lesion may be discovered incidentally during imaging, presenting symptoms may include pain in the affected bone that is exacerbated with physical activity. Laboratory values are normal, and the lesion is not associated with familial skeletal dysplasias. Common imaging findings include a mono-ostotic or polyostotic sclerotic lesion that lacks a periosteal reaction, soft-tissue component, and nidus. We present a case of intramedullary osteosclerosis that was incidentally discovered in a trauma patient.
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http://dx.doi.org/10.2484/rcr.v8i4.878 | DOI Listing |
Cureus
March 2023
Radiology, Hamad General Hospital, Doha, QAT.
Intramedullary osteosclerosis (IMOS) is a rare process of intramedullary bone formation in one or more bones in the lower limb. It arises in adulthood, its etiology is unknown, and it is diagnosed by exclusion. We present a case of a 26-year-old female who presented with three-week history of right tibial pain provoked by prolonged standing.
View Article and Find Full Text PDFBMC Musculoskelet Disord
November 2020
Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takara-machi, Kanazawa-shi, Ishikawa-ken, 920-8641, Japan.
Background: Intramedullary osteosclerosis (IMOS) is a rare condition without specific radiological findings except for the osteosclerotic lesion and is not associated with family history and infection, trauma, or systemic illness. Although the diagnosis of IMOS is confirmed after excluding other osteosclerotic lesions, IMOS is not well known because of its rarity and no specific feature. Therefore, these situations might result in delayed diagnosis.
View Article and Find Full Text PDFJ Arthroplasty
April 2021
Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN.
Background: Osteopetrosis is an inherited bone disease associated with high risk of osteoarthritis and fracture non-union, which can lead to total hip arthroplasty (THA). Bone quality and morphology are altered in these patients, and there are limited data on results of THA in these patients. The goals of this study were to describe implant survivorship, clinical outcomes, radiographic results, and complications in patients with osteopetrosis undergoing primary THA.
View Article and Find Full Text PDFMedicine (Baltimore)
August 2020
Department of Orthopedic Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Gangnam-gu, Seoul.
Rationale: Autosomal dominant type II (AD II) osteopetrosis is a rare inheritable metabolic bone disease characterized by hard but brittle bone and a narrow medullary canal. Intramedullary nailing (IMN) is a difficult but attractive option for the treatment of subtrochanteric fractures in patients with AD II osteopetrosis.
Patient Concerns And Diagnosis: Two patients with AD II osteopetrosis sustained subtrochanteric fractures after a fall.
Bone Joint J
August 2020
Department of Orthopaedic Surgery, Dicle University, Faculty of Medicine, Diyarbakır, Turkey.
Aims: Osteopetrosis (OP) is a rare hereditary disease that causes reduced bone resorption and increased bone density as a result of osteoclastic function defect. Our aim is to review the difficulties, mid-term follow-up results, and literature encountered during the treatment of OP.
Methods: This is a retrospective and observational study containing data from nine patients with a mean age of 14.
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