The signaling pathways and cellular mechanisms that achieve alignment of dorsal and ventral midline structures remain a poorly understood aspect of vertebrate development. In this issue of Developmental Cell, Arraf et al. (2016) find a requisite role for bilaterally symmetrical BMP signaling in coordinating dorsal and ventral tissue morphogenesis.
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| http://dx.doi.org/10.1016/j.devcel.2016.06.007 | DOI Listing |
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