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Investigation of CD47 Expression in Renal Cell Tumors and Evaluation of Its Relationship with Prognostic Parameters.
Diagnostics (Basel)
December 2024
Department of Pathology, Faculty of Medicine, Gaziantep University, 27410 Gaziatep, Turkey.
Renal cell carcinoma is an aggressive form of kidney cancer, contributing to an estimated 138,000 deaths globally in 2017. Traditional treatments like chemotherapy and radiation are generally considered ineffective. Additionally, CD47 has been identified as a crucial tumor antigen involved in the development and progression of various cancers, including renal cell carcinoma.
View Article and Find Full Text PDFPrimary intrarenal hemangioma - A series of 39 cases.
Ann Diagn Pathol
January 2025
Department of Pathology and Laboratory Medicine, Brigham and Women's Hospital, Boston, USA. Electronic address:
Intrarenal hemangiomas lack concise clinicopathologic information, due to the predominance of single case reports and inclusion of other vascular neoplasms and hemangiomas of perirenal, hilar, and renal vein origin. Herein, in this multi-institutional study we evaluate clinicopathologic features of 39 intrarenal hemangiomas. The median age was 62 years (range = 27-94 years; 2:1 male to female ratio), with left-sided predominance (left = 21, right = 13; one case was bilateral).
View Article and Find Full Text PDFSpectrum of Renal Tumors Other Than Renal Cell Carcinoma with Emphasis on Cytomorphological, Immunohistochemical, and Cytogenetic Study.
J Cytol
November 2024
Department of Pathology, Cytogenetics Unit, Kidwai Memorial Institute of Oncology, Bangalore, Karnataka, India.
Background: The role of fine needle aspiration cytology (FNAC) in the diagnosis of renal malignancies is established and has been getting more precise and important over a period of time. Knowledge of the pathology of uncommon renal neoplasms along with radiological and clinical correlations often aids in correct diagnosis.
Aims: The present study aims to describe the cytomorphological and immunohistochemical findings in the varied spectrum of renal tumors, other than renal cell carcinomas (RCC).
TRPS1 Immunohistochemistry in Salivary Gland Neoplasms: Analysis on Cytology Cell Blocks and Surgical Follow-Up Correlation.
Diagn Cytopathol
December 2024
Department of Pathology and Laboratory Medicine, Northwell Health, Donald and Barbara Zucker School of Medicine at Hofstra, Greenvale, New York, USA.
Introduction: In this study we aim to analyze the TRPS1 immunostaining of salivary gland tumors (SGT) on cytology cell blocks and compare the staining pattern on subsequent surgical resections.
Methods: Malignant SGTs, oncocytomas and basal cell adenomas diagnosed on fine needle aspiration were retrieved from 2019 to 2021 database. Cases with surgical follow-up were selected.
Galectin-3 marker expression in renal cell carcinoma and correlation with patient's clinicopathologic factors: A cross-sectional study.
Caspian J Intern Med
October 2024
Cancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Article Synopsis
- Renal Cell Carcinoma (RCC) is a prevalent type of cancer, and this study focused on examining the relationship between galectin-3 expression and various clinical factors in RCC patients.
- A total of 71 patient samples were analyzed for galectin-3 levels through immunohistochemistry, revealing that most patients were male and the majority had clear cell carcinoma.
- The findings suggested that while there was a significant difference in galectin-3 expression between genders, other factors like age and tumor characteristics showed no significant associations, indicating the complexity of galectin's role and the need for more extensive research.
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